PMID- 21574080
OWN - NLM
STAT- MEDLINE
DCOM- 20150511
LR  - 20140416
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 28
IP  - 7
DP  - 2011
TI  - Doxycycline and sulfadimethoxine transfer from cross-contaminated feed to chicken 
      tissues.
PG  - 860-8
LID - 10.1080/19440049.2011.569574 [doi]
AB  - During feed preparation at feed mills or during feed mixing in bins at farms, the 
      accidental contamination of feed at trace levels by veterinary drug residues, 
      commonly known as carry-over, can accidentally but frequently occur. To evaluate 
      the concentrations of residual antimicrobials in poultry edible tissues, due to 
      contaminated feed, sulfadimethoxine and doxycycline were administered for 10 days 
      to chickens in poultry feed incurred at the contamination levels frequently found 
      during national feed monitoring programmes (1-5 mg kg(-1)). Sulfadimethoxine and 
      doxycycline residual concentrations detected in muscle (<LOD and 31 microg kg(-1), 
      respectively), liver (13 and 56 microg kg(-1), respectively) and kidney (56 and 
      115 microg kg(-1), respectively) were compared with their maximum residue limits 
      (MRLs) fixed by EC 470/2009 and EU 37/2010 Regulations for a preliminary risk 
      evaluation.
FAU - Segato, G
AU  - Segato G
AD  - a Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Univerista , 
      10, I-35020 Legnaro (Pd) , Italy.
FAU - Benetti, C
AU  - Benetti C
FAU - Angeletti, R
AU  - Angeletti R
FAU - Montesissa, C
AU  - Montesissa C
FAU - Biancotto, G
AU  - Biancotto G
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110513
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Veterinary Drugs)
RN  - 30CPC5LDEX (Sulfadimethoxine)
RN  - N12000U13O (Doxycycline)
SB  - IM
MH  - Animal Feed/*analysis/toxicity
MH  - Animals
MH  - Chickens/*metabolism
MH  - Doxycycline/*analysis/toxicity
MH  - Drug Residues/analysis/toxicity
MH  - Food Contamination/*analysis/legislation & jurisprudence
MH  - Food Safety
MH  - Humans
MH  - Italy
MH  - Limit of Detection
MH  - Maximum Allowable Concentration
MH  - Sulfadimethoxine/*analysis/toxicity
MH  - Tissue Distribution
MH  - Veterinary Drugs/analysis/toxicity
OTO - NOTNLM
OT  - HPLC
OT  - LC/MS
OT  - animal feedingstuffs
OT  - meat
OT  - risk assessment
OT  - sulphonamides
OT  - tetracycline
OT  - veterinary drug residues
EDAT- 2011/05/17 06:00
MHDA- 2015/05/12 06:00
CRDT- 2011/05/17 06:00
PHST- 2011/05/17 06:00 [entrez]
PHST- 2011/05/17 06:00 [pubmed]
PHST- 2015/05/12 06:00 [medline]
AID - 937581145 [pii]
AID - 10.1080/19440049.2011.569574 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011;28(7):860-8. 
      doi: 10.1080/19440049.2011.569574. Epub 2011 May 13.