PMID- 21589831
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 2036-7503 (Electronic)
IS  - 2036-749X (Print)
IS  - 2036-749X (Linking)
VI  - 2
IP  - 2
DP  - 2010 Sep 6
TI  - Colonic phasic motor activity is stronger in patients with repaired anorectal 
      malformations than patients with severe colonic dismotility.
PG  - e18
LID - 10.4081/pr.2010.e18 [doi]
LID - e18
AB  - In this study, colonic manometry studies of the patients with repaired anorectal 
      malformations (ARM) were compared with those of patients with severe colonic 
      dismotility due to chronic constipation (CC) and acute pseudo-obstruction (PSO). 
      The patients with repaired ARM were accepted as group #1 (n=10). The patients 
      with CC and acute PSO composed group #2 (n=10). Eight-channel water perfused 
      catheter was inserted into the colon under sedation. Colonic activity was 
      recorded in three phases including fasting, after meal and after bisacodyl 
      installation. The results were assessed by Pearson chi(2) test, P<.05 was 
      considered statistically significant. Mean age was 9.6 and 12.1 in groups #1 and 
      #2, respectively. Ninety-five per cent of all patients had propagated 
      contractions (PCs) and 20% and 40% of the patients in group #1 had PCs during 
      fasting and after meal, respectively. These contractions were seen 30% and 70% of 
      the patients in group #2, but no statistical difference was found between the 
      groups. PCs after bisacodyl were observed 90% and 40% of the patients in groups 
      #1 and #2, respectively, and this difference was statistically significant 
      (P=.019). In this study, the prominent difference between the groups was found in 
      response to intraluminal stimulation. This finding may indicate that the colon of 
      the patients with ARM has more capacity to develop PCs by peripheral stimuli and 
      more regular enteric nervous integrity.
FAU - Demirogullari, Billur
AU  - Demirogullari B
AD  - Gazi University Medical Faculty Departments of Pediatric Surgery and Pediatric 
      Gastroenterology, Ankara, Turkey.
FAU - Sari, Sinan
AU  - Sari S
FAU - Egritas, Odul
AU  - Egritas O
FAU - Karakus, Cuneyt
AU  - Karakus C
FAU - Ozen, Io
AU  - Ozen I
FAU - Sonmez, Kaan
AU  - Sonmez K
FAU - Dalgic, Buket
AU  - Dalgic B
FAU - Kale, Nuri
AU  - Kale N
FAU - Basaklar, A Can
AU  - Basaklar AC
LA  - eng
PT  - Journal Article
DEP - 20100906
PL  - Switzerland
TA  - Pediatr Rep
JT  - Pediatric reports
JID - 101551542
PMC - PMC3093997
OTO - NOTNLM
OT  - anorectal malformations
OT  - chronic constipation
OT  - colonic dismotility
OT  - colonic manometry
OT  - pseudo-obstruction.
EDAT- 2010/01/01 00:00
MHDA- 2010/01/01 00:01
PMCR- 2010/09/06
CRDT- 2011/05/19 06:00
PHST- 2010/05/05 00:00 [received]
PHST- 2010/10/21 00:00 [accepted]
PHST- 2011/05/19 06:00 [entrez]
PHST- 2010/01/01 00:00 [pubmed]
PHST- 2010/01/01 00:01 [medline]
PHST- 2010/09/06 00:00 [pmc-release]
AID - pr.2010.2.e18 [pii]
AID - 10.4081/pr.2010.e18 [doi]
PST - epublish
SO  - Pediatr Rep. 2010 Sep 6;2(2):e18. doi: 10.4081/pr.2010.e18.