PMID- 21594489 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20190606 IS - 1021-335X (Print) IS - 1021-335X (Linking) VI - 3 IP - 5 DP - 1996 Sep TI - Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha. PG - 951-5 AB - This study was undertaken to assess the effectiveness of Interferon administered parenterally in the treatment of flat or accuminata condylomata of the female genital tract. One hundred and forty-three women with condylomata were treated with CO2 laser vaporization, 5-FU topical application and interferon alpha-2 alpha (IFN alpha-2 alpha) parenterally. The cure rates in the various treatment groups were analysed by the chi-square test. The cure rates of the treatments used in the patients with condylomata accuminata were similar (p>0.1). The best cure rate for flat condylomata was achieved with the combination of CO2 laser vaporization plus 5-FU plus IFN alpha-2 alpha (high dose) (p<0.01). In conclusion, Interferon can be used as adjuvant treatment in patients with recalcitrant condylomata accuminata and as first line treatment in combination with 5-FU and CO2 laser vaporization in patients with flat condylomata. FAU - Relakis, K AU - Relakis K AD - UNIV HERAKLION,DEPT OBSTET & GYNECOL,IRAKLION,GREECE. UNIV PATRAS,DEPT OBSTET & GYNECOL,PATRAS,GREECE. EUROMED MED INST,ATHENS,GREECE. H VENIZELOU MATERN HOSP,DEPT OBSTET & GYNECOL 4,ATHENS,GREECE. ATHENS NAVAL HOSP,DEPT PATHOL,ATHENS,GREECE. FAU - Cardamakis, E AU - Cardamakis E FAU - Korantzis, A AU - Korantzis A FAU - Kotoulas, I AU - Kotoulas I FAU - Stathopoulos, E AU - Stathopoulos E FAU - Metalinos, K AU - Metalinos K FAU - Papathanasiou, Z AU - Papathanasiou Z FAU - Mantouvalos, H AU - Mantouvalos H FAU - Tzingounis, V AU - Tzingounis V FAU - Koumantakis, E AU - Koumantakis E LA - eng PT - Journal Article PL - Greece TA - Oncol Rep JT - Oncology reports JID - 9422756 EDAT- 1996/09/01 00:00 MHDA- 1996/09/01 00:01 CRDT- 2011/05/20 06:00 PHST- 2011/05/20 06:00 [entrez] PHST- 1996/09/01 00:00 [pubmed] PHST- 1996/09/01 00:01 [medline] AID - 10.3892/or.3.5.951 [doi] PST - ppublish SO - Oncol Rep. 1996 Sep;3(5):951-5. doi: 10.3892/or.3.5.951.