PMID- 21598216
OWN - NLM
STAT- MEDLINE
DCOM- 20110909
LR  - 20220317
IS  - 1735-9694 (Electronic)
IS  - 0044-6025 (Linking)
VI  - 49
IP  - 2
DP  - 2011
TI  - Relation between preoperative mild increased in serum creatinine level and early 
      outcomes after coronary artery bypass grafting.
PG  - 89-92
AB  - This study evaluates the effect of preoperative increased level of serum 
      creatinine (Cr) on early outcomes after coronary artery bypass graft surgery 
      (CABG). 1140 patients who underwent CABG in our center were studied. Patients 
      with Cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were 
      excluded. Group 1 consisted of 892 patients with normal Cr (0.5-1.2 mg/dl) and 
      group 2 consisted of 248 (21.8%) patients with mild increased level of serum Cr 
      (1.3-2.2 mg/dl). Patients in group 1 were younger than group 2. There were more 
      patients with hypertension in group 2, but there were not statistically 
      significant difference between two groups in terms of the frequency of diabetes, 
      smoking, cerebrovascular disease and New York Heart Association (NYHA) class. 
      Left ventricular ejection fraction (LVEF) was lower in group 2. Cardiopulmonary 
      bypass time (CPB) was longer in group 2. Early mortality was 3.2% in group 1 and 
      8.4% in group 2 (P<0.001). Prolonged ICU stay, low cardiac output, prolonged 
      mechanical ventilation, postoperative atrial fibrillation, postoperative 
      re-exploration and sepsis were more frequent in group 2. Mild increase in serum 
      Cr level preoperatively is a marker of increased early mortality and outcome 
      after CABG.
FAU - Radmehr, Hassan
AU  - Radmehr H
AD  - Cardiovascular Surgery Department, Imam Khomeini Medical Center, Tehran 
      University of Medical Sciences, Iran.
FAU - Forouzannia, Seyed Khalil
AU  - Forouzannia SK
FAU - Bakhshandeh, Ali Reza
AU  - Bakhshandeh AR
FAU - Sanatkar, Mehdi
AU  - Sanatkar M
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Acta Med Iran
JT  - Acta medica Iranica
JID - 14540050R
RN  - 0 (Biomarkers)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Biomarkers/blood
MH  - Chi-Square Distribution
MH  - *Coronary Artery Bypass/adverse effects/mortality
MH  - Coronary Artery Disease/blood/mortality/physiopathology/*surgery
MH  - Creatinine/*blood
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Iran
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Preoperative Period
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
MH  - Up-Regulation
EDAT- 2011/05/21 06:00
MHDA- 2011/09/10 06:00
CRDT- 2011/05/21 06:00
PHST- 2011/05/21 06:00 [entrez]
PHST- 2011/05/21 06:00 [pubmed]
PHST- 2011/09/10 06:00 [medline]
AID - 18104 [pii]
PST - ppublish
SO  - Acta Med Iran. 2011;49(2):89-92.