PMID- 21604541 OWN - NLM STAT- MEDLINE DCOM- 20110621 LR - 20110523 IS - 1003-0034 (Print) IS - 1003-0034 (Linking) VI - 24 IP - 4 DP - 2011 Apr TI - [Experimental research progress of warming yang and reinforcing kidney of Chinese medicine to promote the differentiation of bone marrow stromal cells]. PG - 352-6 AB - Bone marrow stromal cells (BMSCs), a kind of stem cells residing in bone marrow, have self-renewal, high proliferative capacity and the potential of multilineage differentiation. It has a good prospect in application of the cell replacement therapy, the gene therapy and the tissue engineering and so on. As the content of BMSCs is extremely low in bone marrow, BM-SCs must be amplified in vitro and induced to differentiation to meet the clinical needs. Researches of the recent years suggest there is a very promising way that Chinese medicine could induce BMSCs proliferation, differentiation. Based on the Chinese medicine theory, "the kidney generating marrow and dominating bone" and "kidney storing essence, essence and marrow", the TCM scholars have done some researches to explore the function of warming yang and reinforcing kidney of Chinese medicine to promote bone marrow stromal cells and found that these drugs can promote the BMSCs to proliferate and to differentiate into osteogenic, cartilage and nerve cells. This article elaborates and presents the researches on this aspect. FAU - Chen, Wei-Heng AU - Chen WH AD - Fujian University of Chinese Medicine, Fuzhou 350108, Fujian, China. FAU - Wang, He-Ming AU - Wang HM LA - chi PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - China TA - Zhongguo Gu Shang JT - Zhongguo gu shang = China journal of orthopaedics and traumatology JID - 9815790 SB - IM MH - Animals MH - Bone Marrow Cells/*cytology MH - Cell Differentiation/drug effects MH - Humans MH - *Medicine, Chinese Traditional MH - Stromal Cells/*cytology EDAT- 2011/05/25 06:00 MHDA- 2011/06/22 06:00 CRDT- 2011/05/25 06:00 PHST- 2011/05/25 06:00 [entrez] PHST- 2011/05/25 06:00 [pubmed] PHST- 2011/06/22 06:00 [medline] PST - ppublish SO - Zhongguo Gu Shang. 2011 Apr;24(4):352-6.