PMID- 21605682
OWN - NLM
STAT- MEDLINE
DCOM- 20111021
LR  - 20220129
IS  - 1095-8657 (Electronic)
IS  - 1047-8477 (Print)
IS  - 1047-8477 (Linking)
VI  - 175
IP  - 2
DP  - 2011 Aug
TI  - Recording information on protein complexes in an information management system.
PG  - 224-9
LID - 10.1016/j.jsb.2011.05.009 [doi]
AB  - The Protein Information Management System (PiMS) is a laboratory information 
      management system (LIMS) designed for use with the production of proteins in a 
      research environment. The software is distributed under the CCP4 licence, and so 
      is available free of charge to academic laboratories. Like most LIMS, the 
      underlying PiMS data model originally had no support for protein-protein 
      complexes. To support the SPINE2-Complexes project the developers have extended 
      PiMS to meet these requirements. The modifications to PiMS, described here, 
      include data model changes, additional protocols, some user interface changes and 
      functionality to detect when an experiment may have formed a complex. Example 
      data are shown for the production of a crystal of a protein complex. Integration 
      with SPINE2-Complexes Target Tracker application is also described.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Savitsky, Marc
AU  - Savitsky M
AD  - Division of Structural Biology, Wellcome Trust Centre for Human Genetics, 
      University of Oxford, Roosevelt Drive, Oxford OX37BN, UK.
FAU - Diprose, Jonathan M
AU  - Diprose JM
FAU - Morris, Chris
AU  - Morris C
FAU - Griffiths, Susanne L
AU  - Griffiths SL
FAU - Daniel, Edward
AU  - Daniel E
FAU - Lin, Bill
AU  - Lin B
FAU - Daenke, Susan
AU  - Daenke S
FAU - Bishop, Benjamin
AU  - Bishop B
FAU - Siebold, Christian
AU  - Siebold C
FAU - Wilson, Keith S
AU  - Wilson KS
FAU - Blake, Richard
AU  - Blake R
FAU - Stuart, David I
AU  - Stuart DI
FAU - Esnouf, Robert M
AU  - Esnouf RM
LA  - eng
GR  - 075491/Z/04/WT_/Wellcome Trust/United Kingdom
GR  - BB/F020228/1/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - BBC5121371/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - G1100525/MRC_/Medical Research Council/United Kingdom
GR  - BBC5121451/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - G0701506/MRC_/Medical Research Council/United Kingdom
GR  - G1000099/MRC_/Medical Research Council/United Kingdom
GR  - BBC5121291/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - 090532/Wellcome Trust/United Kingdom
GR  - G19/3/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110514
PL  - United States
TA  - J Struct Biol
JT  - Journal of structural biology
JID - 9011206
RN  - 0 (Multiprotein Complexes)
SB  - IM
MH  - *Database Management Systems
MH  - Databases, Protein
MH  - Information Management/*methods
MH  - *Multiprotein Complexes/chemistry/genetics
MH  - *Protein Conformation
MH  - User-Computer Interface
MH  - Workflow
PMC - PMC3477311
EDAT- 2011/05/25 06:00
MHDA- 2011/10/22 06:00
PMCR- 2011/08/01
CRDT- 2011/05/25 06:00
PHST- 2011/01/07 00:00 [received]
PHST- 2011/04/29 00:00 [revised]
PHST- 2011/05/07 00:00 [accepted]
PHST- 2011/05/25 06:00 [entrez]
PHST- 2011/05/25 06:00 [pubmed]
PHST- 2011/10/22 06:00 [medline]
PHST- 2011/08/01 00:00 [pmc-release]
AID - S1047-8477(11)00141-9 [pii]
AID - 10.1016/j.jsb.2011.05.009 [doi]
PST - ppublish
SO  - J Struct Biol. 2011 Aug;175(2):224-9. doi: 10.1016/j.jsb.2011.05.009. Epub 2011 
      May 14.