PMID- 21605803
OWN - NLM
STAT- MEDLINE
DCOM- 20110922
LR  - 20110524
IS  - 1558-0520 (Electronic)
IS  - 0733-8635 (Linking)
VI  - 29
IP  - 3
DP  - 2011 Jul
TI  - The genetics of pemphigus.
PG  - 381-91, vii
LID - 10.1016/j.det.2011.03.020 [doi]
AB  - Pemphigus vulgaris (PV) is an autoimmune blistering disorder with a complex 
      etiology involving an interplay of genetic as well as environmental factors, most 
      of which remain unknown. Despite the identification of several human leukocyte 
      antigen (HLA) alleles as risk factors for disease, no other non-HLA genes have 
      clearly been implicated in disease susceptibility. Newer candidate gene and 
      whole-genome approaches are needed to illuminate the full palate of genetic risk 
      elements in PV. Based on this information, genetic-based tools can be expected to 
      provide a scientific rationale for future clinical decision-making by physicians 
      and facilitate an era of personalized medicine.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Sinha, Animesh A
AU  - Sinha AA
AD  - Department of Dermatology, State University of New York at Buffalo and Roswell 
      Park Cancer Institute, MRC 234, Buffalo, NY 14263, USA. asinha@msu.edu
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Dermatol Clin
JT  - Dermatologic clinics
JID - 8300886
SB  - IM
MH  - Autoimmunity/*genetics/immunology
MH  - Genetic Predisposition to Disease/epidemiology/*genetics
MH  - Humans
MH  - Pemphigus/epidemiology/*genetics/immunology
MH  - Risk Factors
EDAT- 2011/05/25 06:00
MHDA- 2011/09/23 06:00
CRDT- 2011/05/25 06:00
PHST- 2011/05/25 06:00 [entrez]
PHST- 2011/05/25 06:00 [pubmed]
PHST- 2011/09/23 06:00 [medline]
AID - S0733-8635(11)00076-3 [pii]
AID - 10.1016/j.det.2011.03.020 [doi]
PST - ppublish
SO  - Dermatol Clin. 2011 Jul;29(3):381-91, vii. doi: 10.1016/j.det.2011.03.020.