PMID- 21616498
OWN - NLM
STAT- MEDLINE
DCOM- 20111003
LR  - 20110708
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1218
IP  - 30
DP  - 2011 Jul 29
TI  - Determination of per- and polyfluorinated substances in airborne particulate 
      matter by microwave-assisted extraction and liquid chromatography-tandem mass 
      spectrometry.
PG  - 4847-55
LID - 10.1016/j.chroma.2011.04.082 [doi]
AB  - A sensitive and confirmatory analytical method has been developed for the 
      determination of 12 ionic per- and polyfluorinated alkyl substances (PFAS) in 
      fine airborne particulate matter (PM2.5) at trace levels. The proposed method 
      includes extraction of PM2.5-bound PFAS by microwave-assisted extraction (MAE) 
      followed by centrifugation and injection into the liquid chromatograph coupled to 
      a triple quadrupole tandem mass spectrometry system (LC-MS/MS). The main 
      parameters affecting the performance of MAE were optimised using statistical 
      design of experiments (DoE). Recoveries ranged from 83 to 120% and the method 
      quantification limit (MQL) was 1.4 pg m(-3), when air volumes of 720 m(3) were 
      sampled. This method was successfully applied to 41 samples collected from five 
      stations of the monitoring network of the Valencian Regional Government (Spain) 
      during April-July 2010. Eight out of 12 PFCs investigated were quantified in at 
      least one sample (PFBA, PFPeA, PFHxS, 6:2 FTS, PFOA, PFNA, PFOS and PFDA). The 
      measured concentrations ranged from 1.4 to 34.3 pg m(-3).
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Beser, Maria Isabel
AU  - Beser MI
AD  - Public Health Research Center of Valencia (CSISP), Valencia, Spain.
FAU - Pardo, Olga
AU  - Pardo O
FAU - Beltran, Joaquim
AU  - Beltran J
FAU - Yusa, Vicent
AU  - Yusa V
LA  - eng
PT  - Journal Article
DEP - 20110525
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Air Pollutants)
RN  - 0 (Fluorocarbons)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - Air Pollutants/*analysis
MH  - Chemical Fractionation/*methods
MH  - Chromatography, Liquid/*methods
MH  - Fluorocarbons/*analysis/chemistry/isolation & purification
MH  - Linear Models
MH  - Microwaves
MH  - Particulate Matter/*chemistry
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Tandem Mass Spectrometry/methods
EDAT- 2011/05/28 06:00
MHDA- 2011/10/04 06:00
CRDT- 2011/05/28 06:00
PHST- 2010/10/22 00:00 [received]
PHST- 2011/02/07 00:00 [revised]
PHST- 2011/04/26 00:00 [accepted]
PHST- 2011/05/28 06:00 [entrez]
PHST- 2011/05/28 06:00 [pubmed]
PHST- 2011/10/04 06:00 [medline]
AID - S0021-9673(11)00608-X [pii]
AID - 10.1016/j.chroma.2011.04.082 [doi]
PST - ppublish
SO  - J Chromatogr A. 2011 Jul 29;1218(30):4847-55. doi: 10.1016/j.chroma.2011.04.082. 
      Epub 2011 May 25.