PMID- 2161867
OWN - NLM
STAT- MEDLINE
DCOM- 19900717
LR  - 20210526
IS  - 0095-1137 (Print)
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Linking)
VI  - 28
IP  - 5
DP  - 1990 May
TI  - Rises in antibody to human herpesvirus 6 detected by enzyme immunoassay in 
      transplant recipients with primary cytomegalovirus infection.
PG  - 851-4
AB  - Immunoglobulin G to human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) in sera 
      from solid organ recipients was measured by an enzyme-linked immunoassay (ELISA) 
      before and after transplant. The HHV-6 ELISA was developed from glycine extracts 
      of HHV-6-infected and uninfected HSB-2 cells. At a serum dilution of 1:500, 80 
      (91%) of 88 recipients were seropositive for HHV-6 before transplant, while only 
      14 (16%) were seropositive for CMV. Posttransplant HHV-6 serologic rises were 
      observed in 38 (43%) recipients; rises in 25 of these recipients were associated 
      with primary CMV infection. Titration of sera revealed much higher HHV-6 titer 
      rises among those with primary CMV infection than among those with CMV 
      reactivation or with no CMV infection. Elevated HHV-6 antibody titers persisted 
      for up to 2 years after primary CMV infection. No correlation was noted between 
      CMV and HHV-6 antibody titers in individual serum samples.
FAU - Chou, S W
AU  - Chou SW
AD  - Medical Service, Veterans Administration Medical Center, Portland, Oregon.
FAU - Scott, K M
AU  - Scott KM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Antibodies, Viral/*metabolism
MH  - Cross Reactions
MH  - Cytomegalovirus/immunology
MH  - Cytomegalovirus Infections/etiology/*immunology
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Herpesviridae/*immunology
MH  - Humans
MH  - Time Factors
MH  - *Transplantation Immunology
PMC - PMC267822
EDAT- 1990/05/01 00:00
MHDA- 1990/05/01 00:01
PMCR- 1990/05/01
CRDT- 1990/05/01 00:00
PHST- 1990/05/01 00:00 [pubmed]
PHST- 1990/05/01 00:01 [medline]
PHST- 1990/05/01 00:00 [entrez]
PHST- 1990/05/01 00:00 [pmc-release]
AID - 10.1128/jcm.28.5.851-854.1990 [doi]
PST - ppublish
SO  - J Clin Microbiol. 1990 May;28(5):851-4. doi: 10.1128/jcm.28.5.851-854.1990.