PMID- 21620126
OWN - NLM
STAT- MEDLINE
DCOM- 20110930
LR  - 20110530
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 43
IP  - 4
DP  - 2011 May
TI  - Non-human leukocyte antigen antibodies reactive with endothelial cells could be 
      involved in early loss of renal allografts.
PG  - 1345-8
LID - 10.1016/j.transproceed.2011.03.059 [doi]
AB  - Preformed donor-specific human leukocyte antigen (HLA) antibodies have been 
      associated with allograft dysfunction and failure. However, recipients of 
      HLA-identical kidneys can develop acute humoral rejection, implicating putative 
      pathogenic antibodies that are directed against non-HLA antigens. We investigated 
      the presence of endothelial cell-reactive antibodies in 11 patients who 
      experienced early loss of their transplanted kidneys owing to humoral rejection 
      and 1 loss from renal venal thrombosis. We examined the potential efficacy of 
      intravenous immunoglobulin to block the binding of these antibodies, as 
      previously suggested for anti-HLA antibodies.
CI  - Copyright (c) 2011. Published by Elsevier Inc.
FAU - Ronda, C
AU  - Ronda C
AD  - Laboratory of Immunology, Heart Institute, School of Medicine, University of Sao 
      Paulo, Sao Paulo, Brazil. cronda51@hotmail.com
FAU - Borba, S C P
AU  - Borba SC
FAU - Ferreira, S C P
AU  - Ferreira SC
FAU - Glotz, D
AU  - Glotz D
FAU - Ianhez, L E
AU  - Ianhez LE
FAU - Rodrigues, H
AU  - Rodrigues H
FAU - Viggiani, C S
AU  - Viggiani CS
FAU - Nahas, W
AU  - Nahas W
FAU - David-Neto, E
AU  - David-Neto E
FAU - Castro, M C R
AU  - Castro MC
FAU - David Daisa, S R
AU  - David Daisa SR
FAU - Kalil, J
AU  - Kalil J
FAU - Panajotopoulos, N
AU  - Panajotopoulos N
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (Antibodies)
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Antibodies/*blood
MH  - Brazil
MH  - Cell Line
MH  - Cytotoxicity Tests, Immunologic
MH  - Endothelial Cells/*immunology
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Flow Cytometry
MH  - Graft Rejection/*immunology
MH  - Histocompatibility Antigens Class I/*immunology
MH  - Histocompatibility Testing
MH  - Humans
MH  - Immunity, Humoral
MH  - Immunoglobulins, Intravenous/metabolism
MH  - Kidney Transplantation/*immunology
MH  - Transplantation, Homologous
MH  - Treatment Outcome
EDAT- 2011/05/31 06:00
MHDA- 2011/10/01 06:00
CRDT- 2011/05/31 06:00
PHST- 2011/05/31 06:00 [entrez]
PHST- 2011/05/31 06:00 [pubmed]
PHST- 2011/10/01 06:00 [medline]
AID - S0041-1345(11)00574-4 [pii]
AID - 10.1016/j.transproceed.2011.03.059 [doi]
PST - ppublish
SO  - Transplant Proc. 2011 May;43(4):1345-8. doi: 10.1016/j.transproceed.2011.03.059.