PMID- 21623246
OWN - NLM
STAT- MEDLINE
DCOM- 20111230
LR  - 20161125
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 69
IP  - 4
DP  - 2011 Oct
TI  - Detection of pulsation in ruptured and unruptured cerebral aneurysms by 
      electrocardiographically gated 3-dimensional computed tomographic angiography 
      with a 320-row area detector computed tomography and evaluation of its clinical 
      usefulness.
PG  - 843-51; discussion 851
LID - 10.1227/NEU.0b013e318225b2d3 [doi]
AB  - BACKGROUND: In ruptured cerebral aneurysms (RCAs), identification of the rupture 
      point of a cerebral aneurysm is useful for treatment planning. In unruptured 
      cerebral aneurysms (URCAs), detection of the risk of aneurysmal rupture is also 
      useful for patient management. OBJECTIVE: Electrocardiographic (ECG)-gated 3D-CT 
      angiography was performed for patients with RCAs and URCAs using 320-row area 
      detector CT (ADCT) to detect pulsation of the cerebral aneurysms. The clinical 
      usefulness of this method was then evaluated. METHODS: Twelve patients had 12 
      RCAs, and 39 patients had 53 URCAs. A 320-row ADCT system was used to scan. 
      ECG-gated reconstruction was then performed with the R-R interval divided into 20 
      phases. RESULTS: Pulsation was observed in 10 of the 12 RCAs. The bleeding site 
      was considered to correspond to the area of pulsation. Pulsation was observed in 
      14 of 53 URCAs. Thirteen patients with 18 URCAs were followed. Of the 11 URCAs in 
      which pulsation was not observed, 1 showed a change in shape. Of the 7 URCAs in 
      which pulsation was observed, 3 showed a change in shape. URCAs in which 
      pulsation was observed were more likely to show a change in shape (P = .082). 
      CONCLUSION: The area of pulsation was found to correspond to the bleeding site in 
      many RCAs. This information would be extremely useful for treatment planning. The 
      detection of pulsation in an URCA is therefore considered to provide useful 
      information for patient management.
FAU - Hayakawa, Motoharu
AU  - Hayakawa M
AD  - Department of Neurosurgery, Fujita Health University, School of Medicine, Aichi, 
      Japan. hayakawa@fujita-hu.ac.jp
FAU - Maeda, Shingo
AU  - Maeda S
FAU - Sadato, Akiyo
AU  - Sadato A
FAU - Tanaka, Teppei
AU  - Tanaka T
FAU - Kaito, Takafumi
AU  - Kaito T
FAU - Hattori, Natsuki
AU  - Hattori N
FAU - Ganaha, Tsukasa
AU  - Ganaha T
FAU - Moriya, Shigeta
AU  - Moriya S
FAU - Katada, Kazuhiro
AU  - Katada K
FAU - Murayama, Kazuhiro
AU  - Murayama K
FAU - Kato, Yoko
AU  - Kato Y
FAU - Hirose, Yuichi
AU  - Hirose Y
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Aneurysm, Ruptured/diagnostic imaging
MH  - Cerebral Angiography/instrumentation/*methods
MH  - Electrocardiography
MH  - Female
MH  - Gated Blood-Pool Imaging/instrumentation/*methods
MH  - Humans
MH  - Imaging, Three-Dimensional/instrumentation/*methods
MH  - Intracranial Aneurysm/*diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Pulsatile Flow/*physiology
EDAT- 2011/05/31 06:00
MHDA- 2011/12/31 06:00
CRDT- 2011/05/31 06:00
PHST- 2011/05/31 06:00 [entrez]
PHST- 2011/05/31 06:00 [pubmed]
PHST- 2011/12/31 06:00 [medline]
AID - 10.1227/NEU.0b013e318225b2d3 [doi]
PST - ppublish
SO  - Neurosurgery. 2011 Oct;69(4):843-51; discussion 851. doi: 
      10.1227/NEU.0b013e318225b2d3.