PMID- 21624075
OWN - NLM
STAT- MEDLINE
DCOM- 20110929
LR  - 20110531
IS  - 1744-9987 (Electronic)
IS  - 1744-9979 (Linking)
VI  - 15
IP  - 3
DP  - 2011 Jun
TI  - Forty-eight-hour ambulatory blood pressure and carotid-femoral pulse wave 
      velocity in hemodialysis patients.
PG  - 273-7
LID - 10.1111/j.1744-9987.2011.00950.x [doi]
AB  - Carotid-femoral pulse wave velocity (cfPWV) is an important predictor of 
      cardiovascular events in the general population and also in hemodialysis (HD) 
      patients. In the general population, cfPWV is strongly associated with age and 
      blood pressure (BP). The best timing and method of BP measurement in HD patients 
      is uncertain. Ambulatory blood pressure measurements (ABPM) have been used to 
      better define the relationship between BP, target organ damage, and outcomes in 
      HD patients. The aim of this study was to determine the possible association 
      between cfPWV, cardiovascular risk factors, single BP measurements, and 48-hour 
      ABPM in chronic HD patients. Thirty-three HD patients (22 men, 11 women) were 
      included. After the end of the mid-week HD session, BP was measured, arterial 
      stiffness was estimated by cfPWV, and 48-hour ABPM was performed. The mean 
      systolic and diastolic BP readings before cfPWV measurement were 136/79 mmn Hg, 
      and the mean 48-hour systolic and diastolic BP readings were 131/76 mm Hg. The 
      mean and range of the cfPWV measurements were 8.31 +/- 2.35 m/s and 5.18-16.53 m/s, 
      respectively. Using regression analysis, no association between cfPWV and BP 
      before PWV measurements was found. A statistically significant correlation 
      between cfPWV and 48-hour systolic and diastolic ABPM was found. Using multiple 
      regression analysis (including age, sex, smoking, diabetes, body mass index, 
      total cholesterol, low- and high-density lipoprotein cholesterol, triglycerides, 
      C-reactive protein, albumin, phosphorus, calcium, and iPTH) 48-hour systolic (P < 
      0.001) and diastolic ABPM (P < 0.005) still remain significantly associated with 
      cfPWV. Only 48-hour ABPM was associated with cfPWV in HD patients in our study. 
      We found no relationship between cfPWV and other cardiovascular risk factors.
CI  - (c) 2011 The Authors. Therapeutic Apheresis and Dialysis (c) 2011 International 
      Society for Apheresis.
FAU - Ekart, Robert
AU  - Ekart R
AD  - Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia. 
      robert.ekart2@guest.arnes.si
FAU - Bernhardt, Matej
AU  - Bernhardt M
FAU - Balon, Breda Pecovnik
AU  - Balon BP
FAU - Bevc, Sebastjan
AU  - Bevc S
FAU - Hojs, Radovan
AU  - Hojs R
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Ther Apher Dial
JT  - Therapeutic apheresis and dialysis : official peer-reviewed journal of the 
      International Society for Apheresis, the Japanese Society for Apheresis, the 
      Japanese Society for Dialysis Therapy
JID - 101181252
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Flow Velocity
MH  - *Blood Pressure
MH  - Blood Pressure Monitoring, Ambulatory/methods
MH  - Cardiovascular Diseases/*etiology/physiopathology
MH  - Carotid Arteries/metabolism/pathology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Femoral Artery/metabolism/pathology
MH  - Humans
MH  - Kidney Failure, Chronic/*therapy
MH  - Male
MH  - Middle Aged
MH  - Regression Analysis
MH  - *Renal Dialysis
MH  - Risk Factors
MH  - Young Adult
EDAT- 2011/06/01 06:00
MHDA- 2011/10/01 06:00
CRDT- 2011/06/01 06:00
PHST- 2011/06/01 06:00 [entrez]
PHST- 2011/06/01 06:00 [pubmed]
PHST- 2011/10/01 06:00 [medline]
AID - 10.1111/j.1744-9987.2011.00950.x [doi]
PST - ppublish
SO  - Ther Apher Dial. 2011 Jun;15(3):273-7. doi: 10.1111/j.1744-9987.2011.00950.x.