PMID- 21627975
OWN - NLM
STAT- MEDLINE
DCOM- 20120612
LR  - 20120220
IS  - 1873-507X (Electronic)
IS  - 0031-9384 (Linking)
VI  - 106
IP  - 1
DP  - 2012 Apr 12
TI  - Obesity: the allostatic load of weight loss dieting.
PG  - 16-21
LID - 10.1016/j.physbeh.2011.05.020 [doi]
AB  - The obesity epidemic that is prevailing in most countries of the world is 
      generally attributed to the increased amount of opportunities to be in positive 
      energy balance in a context of modernity. This obviously refers not only to 
      sedentariness and unhealthy eating that may dominate life habits of many 
      individuals but also to unsuspected non-caloric factors which produce discrete 
      allostatic changes in the body. In this paper, the focus is put on the impact of 
      some of these factors with the preoccupation to document the allostatic burden of 
      weight loss. Thus, beyond the fact that modernity favors opportunities to eat 
      much and not to be active, the proposed conceptual integration leads to the 
      conclusion that a modern lifestyle makes weight loss more difficult for obese 
      individuals. In addition to the natural effects of weight loss favoring 
      resistance to lose fat, a lifestyle promoting shorter sleep duration and more 
      cognitive demand produces allostatic changes that may interfere with weight loss. 
      The case of persistent organic pollutants (POPs) is also discussed as an example 
      of the potential detrimental effects of a contaminated environment on metabolic 
      processes involved in the control of energy expenditure. Taken together, these 
      observations suggest that weight loss is more than ever a search for compromise 
      between its metabolic benefits and its allostatic effects promoting body weight 
      regain.
CI  - Copyright A(c) 2011 Elsevier Inc. All rights reserved.
FAU - Tremblay, Angelo
AU  - Tremblay A
AD  - Division of Kinesiology, Faculty of Medicine, Laval University, Quebec City, QC, 
      Canada, G1V 0A6. angelo.tremblay@kin.msp.ulaval.ca
FAU - Chaput, Jean-Philippe
AU  - Chaput JP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20110524
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
RN  - 0 (Blood Glucose)
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Allostasis/*physiology
MH  - Blood Glucose/metabolism
MH  - Body Weight/physiology
MH  - *Diet, Reducing/adverse effects
MH  - Eating/physiology
MH  - Environment
MH  - Environmental Pollutants/adverse effects
MH  - Humans
MH  - Hypoglycemia/etiology
MH  - Obesity/*diet therapy/*physiopathology
MH  - Respiratory Mechanics/physiology
MH  - Weight Loss/*physiology
EDAT- 2011/06/02 06:00
MHDA- 2012/06/13 06:00
CRDT- 2011/06/02 06:00
PHST- 2011/03/30 00:00 [received]
PHST- 2011/05/11 00:00 [revised]
PHST- 2011/05/16 00:00 [accepted]
PHST- 2011/06/02 06:00 [entrez]
PHST- 2011/06/02 06:00 [pubmed]
PHST- 2012/06/13 06:00 [medline]
AID - S0031-9384(11)00270-8 [pii]
AID - 10.1016/j.physbeh.2011.05.020 [doi]
PST - ppublish
SO  - Physiol Behav. 2012 Apr 12;106(1):16-21. doi: 10.1016/j.physbeh.2011.05.020. Epub 
      2011 May 24.