PMID- 21631360
OWN - NLM
STAT- MEDLINE
DCOM- 20111021
LR  - 20211020
IS  - 1557-7600 (Electronic)
IS  - 1096-620X (Print)
IS  - 1096-620X (Linking)
VI  - 14
IP  - 7-8
DP  - 2011 Jul-Aug
TI  - The effects of powdered fertilized eggs on depression.
PG  - 870-5
LID - 10.1089/jmf.2010.0146 [doi]
AB  - This 12-week, double-blind, placebo-controlled study investigated the effects of 
      fertilized egg powder (Young Tissue Extract; YT(R)) intake on outcome measures for 
      depression. Fifty-five patients with depression were randomly assigned to receive 
      YTE, YTE plus Melissa officinalis, or placebo for 12 weeks. At baseline, there 
      were no significant differences in scores on the Hamilton Depression Rating Scale 
      (HAM-D) or Beck Depression Inventory II (BDI-II) among the 3 groups. At 12 weeks, 
      the HAM-D scores in groups treated with YTE or YTE with M. officinalis were both 
      significantly lower than those in the placebo group. In addition, both treatment 
      groups showed a significant improvement in depression as measured by the change 
      in HAM-D scores from baseline to 12 weeks, whereas the placebo group showed no 
      significant change. There were no significant differences between the 2 treatment 
      groups. The study indicates that the fertilized egg powder has an antidepressive 
      effect and may be an alternative or adjunct to antidepressive medication for some 
      patients, but further research is necessary.
FAU - Solberg, Ester
AU  - Solberg E
AD  - Department for Drug Abuse and Psychiatry, Blefjell Hospital, Kongsberg, Norway. 
      est-skr@online.no
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20110601
PL  - United States
TA  - J Med Food
JT  - Journal of medicinal food
JID - 9812512
RN  - 0 (Antidepressive Agents)
RN  - 0 (Plant Extracts)
RN  - 0 (Powders)
RN  - 0 (Tissue Extracts)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Animals
MH  - Antidepressive Agents/*therapeutic use
MH  - Chickens
MH  - Depression/*drug therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Melissa/chemistry
MH  - Middle Aged
MH  - Plant Extracts/therapeutic use
MH  - Powders
MH  - Tissue Extracts/*therapeutic use
MH  - Treatment Outcome
MH  - Zygote/*chemistry
PMC - PMC3133680
EDAT- 2011/06/03 06:00
MHDA- 2011/10/22 06:00
PMCR- 2011/07/01
CRDT- 2011/06/03 06:00
PHST- 2011/06/03 06:00 [entrez]
PHST- 2011/06/03 06:00 [pubmed]
PHST- 2011/10/22 06:00 [medline]
PHST- 2011/07/01 00:00 [pmc-release]
AID - 10.1089/jmf.2010.0146 [pii]
AID - 10.1089/jmf.2010.0146 [doi]
PST - ppublish
SO  - J Med Food. 2011 Jul-Aug;14(7-8):870-5. doi: 10.1089/jmf.2010.0146. Epub 2011 Jun 
      1.