PMID- 21638287
OWN - NLM
STAT- MEDLINE
DCOM- 20111118
LR  - 20211020
IS  - 1932-8737 (Electronic)
IS  - 0160-9289 (Print)
IS  - 0160-9289 (Linking)
VI  - 34
IP  - 7
DP  - 2011 Jul
TI  - Effect of cardiac resynchronization therapy on libido and erectile dysfunction.
PG  - 437-41
LID - 10.1002/clc.20918 [doi]
AB  - BACKGROUND: Chronic heart failure (HF) is a common, complex clinical syndrome 
      characterized by dyspnea, fatigue and exercise intolerance. HF patients 
      experience decreased libido and erectile dysfunction (ED). The effects of cardiac 
      resynchronization therapy (CRT) on libido and erectile function have not been 
      previously evaluated. We aimed to investigate the effects of CRT on libido and 
      ED. HYPOTHESIS: Cardiac resynchronization therapy improves libido and ED. 
      METHODS: Thirty-one male patients with advanced HF, scheduled for implantation of 
      a CRT device, were included in the study. Left ventricular systolic function, New 
      York Heart Association (NYHA) class, libido, and ED were assessed before and 6 
      months after CRT. Libido and ED were evaluated with the Aging Male Symptoms (AMS) 
      rating scale and internationally validated Sexual Health Inventory for Men (SHIM) 
      questionnaire, respectively. RESULTS: At the 6-month follow-up, the mean NYHA 
      class improved from 3.4 +/- 0.5 to 2.1 +/- 0.6 (P<0.001). On echocardiographic 
      examination, an improvement in left ventricular ejection fraction (LVEF) from 18 
      +/- 5% to 32 +/- 6% was detected (P<0.001). A significant increase in mean SHIM score 
      and a significant decrease in mean AMS were noted. Changes in SHIM and AMS scores 
      were correlated positively with the increase in LVEF (r = 0.47, P = 0.007 and r = 
      - 0.36, P = 0.04, respectively). Similarly, SHIM scores were correlated 
      negatively (r = - 0.57, P = 0.001) and AMS scores were correlated positively (r = 
      0.73, P = 0.0001) with the improvement in NYHA class. CONCLUSIONS: CRT results in 
      a significant improvement in libido and erectile function in patients with 
      congestive HF. This improvement is related to the improvements in the LVEF and 
      functional capacity. .
CI  - (c) 2011 Wiley Periodicals, Inc.
FAU - Vural, Ahmet
AU  - Vural A
AD  - Department of Cardiology, Kocaeli University Medical Faculty, Kocaeli, Turkey.
FAU - Agacdiken, Aysen
AU  - Agacdiken A
FAU - Celikyurt, Umut
AU  - Celikyurt U
FAU - Culha, Melih
AU  - Culha M
FAU - Kahraman, Goksel
AU  - Kahraman G
FAU - Kozdag, Guliz
AU  - Kozdag G
FAU - Ural, Dilek
AU  - Ural D
LA  - eng
PT  - Journal Article
DEP - 20110602
PL  - United States
TA  - Clin Cardiol
JT  - Clinical cardiology
JID - 7903272
SB  - IM
MH  - *Cardiac Resynchronization Therapy
MH  - Chronic Disease
MH  - Erectile Dysfunction/*etiology/physiopathology
MH  - Heart Failure/complications/diagnostic 
      imaging/physiopathology/psychology/*therapy
MH  - Humans
MH  - *Libido
MH  - Male
MH  - Middle Aged
MH  - Recovery of Function
MH  - Stroke Volume
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Treatment Outcome
MH  - Turkey
MH  - Ultrasonography
MH  - Ventricular Function, Left
PMC - PMC6652690
EDAT- 2011/06/04 06:00
MHDA- 2011/12/13 00:00
PMCR- 2011/06/02
CRDT- 2011/06/04 06:00
PHST- 2010/12/23 00:00 [received]
PHST- 2011/03/16 00:00 [accepted]
PHST- 2011/06/04 06:00 [entrez]
PHST- 2011/06/04 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
PHST- 2011/06/02 00:00 [pmc-release]
AID - CLC20918 [pii]
AID - 10.1002/clc.20918 [doi]
PST - ppublish
SO  - Clin Cardiol. 2011 Jul;34(7):437-41. doi: 10.1002/clc.20918. Epub 2011 Jun 2.