PMID- 21641353 OWN - NLM STAT- MEDLINE DCOM- 20110823 LR - 20161125 IS - 1097-6744 (Electronic) IS - 0002-8703 (Linking) VI - 161 IP - 6 DP - 2011 Jun TI - Late gadolinium enhancement on cardiac magnetic resonance and phenotypic expression in hypertrophic cardiomyopathy. PG - 1073-7 LID - 10.1016/j.ahj.2011.03.022 [doi] AB - BACKGROUND: Cardiac magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) can identify areas of myocardial fibrosis in vivo in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to examine the association between clinical-morphological variables, risk factor for sudden death, and LGE findings in a consecutive, unselected population of HCM patients. METHODS: From January 2005 to August 2009, 124 HCM patients (53 +/- 17 years, 86 men) were prospectively evaluated with CMR examination, assessing left ventricular (LV) hypertrophy, function, and LGE. RESULTS: In univariate analysis, patients were divided into tertiles according to the number of segments positive for LGE (first tertile, 0.3 +/- 0.4; second tertile, 2.2 +/- 0.4; third tertile, 5.2 +/- 1.9 segments). Male gender (P = .05), maximum LV wall thickness (P = .002), nonsustained ventricular tachycardia (P = .001), ejection fraction <50% (P = .02), LV mass (P = .02), left atrium dilation (P = .04), perfusion defects (P