PMID- 21643914 OWN - NLM STAT- MEDLINE DCOM- 20110923 LR - 20110606 IS - 1940-6029 (Electronic) IS - 1064-3745 (Linking) VI - 747 DP - 2011 TI - The LC-MS/MS methods for the determination of specific antibiotics residues in food matrices. PG - 309-55 LID - 10.1007/978-1-61779-136-9_13 [doi] AB - This chapter describes the LC-MS/MS methods for the determination of antibiotics residues in food matrices. The types of antibiotics include beta-lactam antibiotics, sulfonamides, tetracyclines, fluoroquinolones, nitrofurans, and chloramphenicol (CAP). The food matrices are mainly from animal origin, such as animal tissues, fishes (marine products), eggs, milk, honey, and so on. The methods and procedures are covered, including three parts: (1) Liquid chromatographic conditions, (2) mass spectrometer conditions, including ionization source, analyzer, and acquisition, and (3) extraction and clean-up methods. In each case, the standard operating procedures (SOPs) for analysis are given with sensitivity, linearity, precision, and recovery. Some criteria of maximum residue limits (MRLs) from the legislation are listed. FAU - Chen, Gui-Liang AU - Chen GL AD - Shanghai Institute for Food and Drug Control, Shanghai, China. chenguiliang@smda.gov.cn FAU - Fang, Yan-Yan AU - Fang YY LA - eng PT - Journal Article PL - United States TA - Methods Mol Biol JT - Methods in molecular biology (Clifton, N.J.) JID - 9214969 RN - 0 (Anti-Bacterial Agents) SB - IM MH - Anti-Bacterial Agents/*analysis MH - Chromatography, Liquid/*methods MH - Drug Residues/*analysis MH - Solid Phase Extraction MH - Tandem Mass Spectrometry/*methods EDAT- 2011/06/07 06:00 MHDA- 2011/09/29 06:00 CRDT- 2011/06/07 06:00 PHST- 2011/06/07 06:00 [entrez] PHST- 2011/06/07 06:00 [pubmed] PHST- 2011/09/29 06:00 [medline] AID - 10.1007/978-1-61779-136-9_13 [doi] PST - ppublish SO - Methods Mol Biol. 2011;747:309-55. doi: 10.1007/978-1-61779-136-9_13.