PMID- 21664693
OWN - NLM
STAT- MEDLINE
DCOM- 20120719
LR  - 20181201
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Linking)
VI  - 42
DP  - 2012 Jul
TI  - Determination of polybrominated diphenyl ethers in human semen.
PG  - 132-7
LID - 10.1016/j.envint.2011.05.011 [doi]
AB  - Some persistent organic pollutants (POPs) have been found in human semen but 
      until this point it was unclear whether polybrominated diphenyl ethers (PBDEs) 
      could be detected in human semen. In this study, PBDEs were found for the first 
      time in human semen samples (n=101) from Taizhou, China. The concentrations of 
      total PBDEs ( summation operatorPBDEs) varied from 15.8 to 86.8 pg/g ww (median=31.3 pg/g ww) and 
      53.2 to 121 pg/g ww (median=72.3 pg/g ww) in semen and blood samples, 
      respectively. The  summation operatorPBDE level in semen was about two times lower than in human 
      blood, which was different in the distribution in the two matrices from other 
      POPs. A correlation of  summation operatorPBDE concentration was found between paired semen and in 
      blood. The results suggest that semen could be used to detect PBDE burden in 
      human body as a non-invasive matrix. In addition, the levels of BDE-209 and 
      BDE-153, especially the latter, were much higher in blood than in semen, while 
      the levels of BDE-28, BDE-47 and BDE-99 were comparable in the two matrices, 
      suggesting that low brominated congeners could be more easily transferred to 
      semen than high brominated congeners. Considering different toxicities among the 
      PBDE congeners, it might be more significant to measure PBDEs in semen than in 
      blood for evaluating male reproduction risks of PBDEs.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Liu, Peng-Yan
AU  - Liu PY
AD  - College of Chemistry and Environmental Science, HeBei University, Baoding, Hebei, 
      China.
FAU - Zhao, Ya-Xian
AU  - Zhao YX
FAU - Zhu, Yi-Yang
AU  - Zhu YY
FAU - Qin, Zhan-Fen
AU  - Qin ZF
FAU - Ruan, Xian-Li
AU  - Ruan XL
FAU - Zhang, Yong-Chuan
AU  - Zhang YC
FAU - Chen, Bao-Jun
AU  - Chen BJ
FAU - Li, Yan
AU  - Li Y
FAU - Yan, Shi-Shuai
AU  - Yan SS
FAU - Qin, Xiao-Fei
AU  - Qin XF
FAU - Fu, Shan
AU  - Fu S
FAU - Xu, Xiao-Bai
AU  - Xu XB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110612
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (2,2',4,4',5-brominated diphenyl ether)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Polybrominated Biphenyls)
RN  - 0 (hexabrominated diphenyl ether 153)
RN  - 0N97R5X10X (2,2',4,4'-tetrabromodiphenyl ether)
RN  - 7REL09ZX35 (pentabromodiphenyl ether)
RN  - MID70C8XSX (tribromodiphenyl ether 28)
RN  - N80BQ29A0H (decabromobiphenyl ether)
SB  - IM
MH  - Adult
MH  - China
MH  - Environmental Exposure/*statistics & numerical data
MH  - Environmental Pollutants/*metabolism
MH  - Gas Chromatography-Mass Spectrometry
MH  - Halogenated Diphenyl Ethers/*metabolism
MH  - Humans
MH  - Male
MH  - Polybrominated Biphenyls/metabolism
MH  - Semen/*metabolism
MH  - Young Adult
EDAT- 2011/06/15 06:00
MHDA- 2012/07/20 06:00
CRDT- 2011/06/14 06:00
PHST- 2010/09/21 00:00 [received]
PHST- 2011/04/17 00:00 [revised]
PHST- 2011/05/17 00:00 [accepted]
PHST- 2011/06/14 06:00 [entrez]
PHST- 2011/06/15 06:00 [pubmed]
PHST- 2012/07/20 06:00 [medline]
AID - S0160-4120(11)00156-5 [pii]
AID - 10.1016/j.envint.2011.05.011 [doi]
PST - ppublish
SO  - Environ Int. 2012 Jul;42:132-7. doi: 10.1016/j.envint.2011.05.011. Epub 2011 Jun 
      12.