PMID- 21666522
OWN - NLM
STAT- MEDLINE
DCOM- 20120131
LR  - 20110928
IS  - 1538-9235 (Electronic)
IS  - 1040-5488 (Linking)
VI  - 88
IP  - 10
DP  - 2011 Oct
TI  - Corneal sublayer thickness measurements with the Nidek ConfoScan 4 (z Ring).
PG  - E1240-4
LID - 10.1097/OPX.0b013e318223bf20 [doi]
AB  - PURPOSE: To determine the repeatability of corneal sublayer thickness 
      measurements using the Nidek ConfoScan 4 (CS4) with the z ring on a group of 
      young adult subjects. METHODS: Thirty subjects aged 18 to 30 years were invited 
      to have thickness measurements with the CS4 (z ring) on two different days, at 
      similar time of the day to avoid diurnal variation. RESULTS: Only 22 subjects had 
      valid measurements for analysis. The mean +/- SD of central corneal thickness (CCT) 
      was 534 +/- 26 mum, epithelial thickness was 42 +/- 8 mum, Bowman's layer thickness was 
      19 +/- 7 mum, and stromal thickness (ST) was 472 +/- 25 mum. There was no significant 
      difference in the between-visit thickness measurements of each layer with the CS4 
      (z ring) (paired t-tests, p > 0.05). The limits of agreement of between-visit 
      measurements were -41 (8%) to 37 mum (7%) for CCT, -21 (50%) to 19 mum (45%) for 
      epithelial thickness, -13 (68%) to 17 mum (89%) for Bowman layer thickness, and 
      -46 (10%) to 37 mum (8%) for ST. CONCLUSIONS: Measurements of CCT and ST with the 
      CS4 (z ring) showed reasonably good repeatability (7 to 10%). However, the 
      repeatability of measurements of the thinner corneal layers, such as epithelium 
      and Bowman's layer, was poor.
FAU - Chan, Ka Yin
AU  - Chan KY
AD  - School of Optometry, The Hong Kong Polytechnic University, Hung Hom, Kowloon, 
      Hong Kong. so.dede@polyu.edu.hk
FAU - Cheung, Sin Wan
AU  - Cheung SW
FAU - Lam, Andrew K C
AU  - Lam AK
FAU - Cho, Pauline
AU  - Cho P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Optom Vis Sci
JT  - Optometry and vision science : official publication of the American Academy of 
      Optometry
JID - 8904931
SB  - IM
MH  - Adult
MH  - Bowman Membrane/*cytology
MH  - Epithelium, Corneal/*cytology
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - Male
MH  - Microscopy, Confocal/*instrumentation
MH  - Reference Values
MH  - Reproducibility of Results
MH  - Young Adult
EDAT- 2011/06/15 06:00
MHDA- 2012/02/01 06:00
CRDT- 2011/06/14 06:00
PHST- 2011/06/14 06:00 [entrez]
PHST- 2011/06/15 06:00 [pubmed]
PHST- 2012/02/01 06:00 [medline]
AID - 10.1097/OPX.0b013e318223bf20 [doi]
PST - ppublish
SO  - Optom Vis Sci. 2011 Oct;88(10):E1240-4. doi: 10.1097/OPX.0b013e318223bf20.