PMID- 21676851
OWN - NLM
STAT- Publisher
LR  - 20240227
IS  - 1531-1937 (Electronic)
IS  - 0897-1900 (Linking)
DP  - 2011 Jun 6
TI  - Evaluation of the Implementation of an Anticoagulation Management Protocol at a 
      Community Hospital.
AB  - Purpose: The objective of this study was to evaluate the impact of implementation 
      of an anticoagulation protocol involving dosing and monitoring of unfractionated 
      heparin (UFH) and low-molecular-weight heparin, specifically enoxaparin, for the 
      treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), and/or acute 
      coronary syndromes (ACS). Methods: Patients with a primary diagnosis of DVT, PE, 
      and/or ACS treated with UFH and/or enoxaparin were included. Data were collected 
      on patients admitted to a community hospital during February 2008 
      (preimplementation) and February 2009 (postimplementation). Results: Forty-six 
      patients were included in the preimplementation group and 25 patients in the 
      postimplementation group. Forty-six percent of patients were dosed properly in 
      the preimplementation group (UFH 38% and enoxaparin 50%) compared to 76% in the 
      postimplementation group (UFH 56% and enoxaparin 88%; P = .023). Fifty-four 
      percent of patients were monitored properly in the preimplementation group (UFH 
      31% and enoxaparin 67%) compared to 68% in the postimplementation group (UFH 56% 
      and enoxaparin 75%; P = .318). Conclusion: Standardized dosing with a 
      multidisciplinary-managed anticoagulation protocol significantly increased proper 
      dosing of anticoagulation therapy; however, the protocol did not significantly 
      improve proper monitoring. A lack of understanding of the need for baseline 
      laboratory data contributes to improper monitoring. An approach which includes 
      significant educational strategies is necessary to optimize patient care.
FAU - Crannage, Andrew J
AU  - Crannage AJ
AD  - Department of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis.
FAU - Murphy, Julie A
AU  - Murphy JA
LA  - eng
PT  - Journal Article
DEP - 20110606
PL  - United States
TA  - J Pharm Pract
JT  - Journal of pharmacy practice
JID - 8900945
EDAT- 2011/06/17 06:00
MHDA- 2011/06/17 06:00
CRDT- 2011/06/17 06:00
PHST- 2011/06/17 06:00 [entrez]
PHST- 2011/06/17 06:00 [pubmed]
PHST- 2011/06/17 06:00 [medline]
AID - 0897190011406124 [pii]
AID - 10.1177/0897190011406124 [doi]
PST - aheadofprint
SO  - J Pharm Pract. 2011 Jun 6. doi: 10.1177/0897190011406124.