PMID- 21680845
OWN - NLM
STAT- MEDLINE
DCOM- 20121101
LR  - 20120214
IS  - 1460-2199 (Electronic)
IS  - 1047-3211 (Linking)
VI  - 22
IP  - 3
DP  - 2012 Mar
TI  - Valuing one's self: medial prefrontal involvement in epistemic and emotive 
      investments in self-views.
PG  - 659-67
LID - 10.1093/cercor/bhr144 [doi]
AB  - Recent neuroimaging research has revealed that the medial prefrontal cortex 
      (MPFC) is consistently engaged when people form mental representations of 
      themselves. However, the precise function of this region in self-representation 
      is not yet fully understood. Here, we investigate whether the MPFC contributes to 
      epistemic and emotive investments in self-views, which are essential components 
      of the self-concept that stabilize self-views and shape how one feels about 
      oneself. Using functional magnetic resonance imaging, we show that the level of 
      activity in the MPFC when people think about their personal traits (by judging 
      trait adjectives for self-descriptiveness) depends on their investments in the 
      particular self-view under consideration, as assessed by postscan rating scales. 
      Furthermore, different forms of investments are associated with partly distinct 
      medial prefrontal areas: a region of the dorsal MPFC is uniquely related to the 
      degree of certainty with which a particular self-view is held (one's epistemic 
      investment), whereas a region of the ventral MPFC responds specifically to the 
      importance attached to this self-view (one's emotive investment). These findings 
      provide new insight into the role of the MPFC in self-representation and suggest 
      that the ventral MPFC confers degrees of value upon the particular conception of 
      the self that people construct at a given moment.
FAU - D'Argembeau, Arnaud
AU  - D'Argembeau A
AD  - Department of Cognitive Sciences, University of Liege, 4000 Liege, Belgium. 
      a.dargembeau@ulg.ac.be
FAU - Jedidi, Haroun
AU  - Jedidi H
FAU - Balteau, Evelyne
AU  - Balteau E
FAU - Bahri, Mohamed
AU  - Bahri M
FAU - Phillips, Christophe
AU  - Phillips C
FAU - Salmon, Eric
AU  - Salmon E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110616
PL  - United States
TA  - Cereb Cortex
JT  - Cerebral cortex (New York, N.Y. : 1991)
JID - 9110718
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect/*physiology
MH  - Awareness/physiology
MH  - Brain Mapping/methods
MH  - Emotions/*physiology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Neuropsychological Tests
MH  - Personality/*physiology
MH  - Prefrontal Cortex/*physiology
MH  - *Self-Assessment
MH  - Young Adult
EDAT- 2011/06/18 06:00
MHDA- 2012/11/02 06:00
CRDT- 2011/06/18 06:00
PHST- 2011/06/18 06:00 [entrez]
PHST- 2011/06/18 06:00 [pubmed]
PHST- 2012/11/02 06:00 [medline]
AID - bhr144 [pii]
AID - 10.1093/cercor/bhr144 [doi]
PST - ppublish
SO  - Cereb Cortex. 2012 Mar;22(3):659-67. doi: 10.1093/cercor/bhr144. Epub 2011 Jun 
      16.