PMID- 21683369
OWN - NLM
STAT- MEDLINE
DCOM- 20110920
LR  - 20151119
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1218
IP  - 29
DP  - 2011 Jul 22
TI  - Sensitive determination of phenylarsenic compounds based on a dual 
      preconcentration method with capillary electrophoresis/UV detection.
PG  - 4779-87
LID - 10.1016/j.chroma.2011.05.058 [doi]
AB  - A novel method based on off-line hollow fiber based liquid liquid liquid 
      microextraction (HF-LLLME) combined with on-column anion selective exhaustive 
      injection (ASEI)-capillary electrophoresis/ultraviolet (CE/UV) detection was 
      proposed for the speciation of five phenylarsenic compounds including 
      phenylarsonic acid (PAA), 4-aminophenylarsonic acid (4-APAA), 
      4-hydroxyphenylarsonic acid (4-HPAA), 4-nitrophenylarsonic acid (4-NPAA) and 
      3-nitro-4-hydroxyphenylarsonic acid (NHPAA) in this paper. In HF-LLLME, the 
      target analytes were extracted from 5 mL aqueous samples (donor solution pH 2.15) 
      through a thin phase of tributyl phosphate (TBP) inside the pores of a 
      polypropylene hollow fiber and finally into an 18 muL 0.8 mmol/L Tris acceptor 
      solution inside the lumen of the hollow fiber. Following HF-LLLME, the acceptor 
      solutions were directly analyzed by ASEI-CE/UV. For ASEI, a large plug of water 
      (91% length of total capillary) was introduced into the separation capillary 
      before sample injection in order to prolong the sample injection time, and thus 
      enhance the stacking efficiency. Under the optimized ASEI conditions, up to 
      236-fold of enrichment factor (EF) was obtained for the ASEI-CE/UV determination 
      of target phenylarsenic compounds. By combining HF-LLLME with ASEI-CE/UV, EFs 
      ranging from 155 to 1780-fold were achieved and the limits of detection (LODs) 
      (at a signal-to-noise ratio of 3) were in the range of 0.68-6.90 mug/L for five 
      phenylarsenic compounds; the relative standard deviations (RSDs) of corrected 
      peak area were 5.6-11.8%. The proposed HF-LLLME-ASEI-CE/UV method was applied for 
      the determination of five target phenylarsenic compounds in pig feed from a local 
      pig farm, and storage pig litter, soil in agricultural field and lake water 
      collected near this pig farm, the recoveries for the spiked samples were in the 
      range of 85.7-104.5%, 66.7-96.2%, 28.9-46.9% and 86.9-107.8% for pig feed, pig 
      litter, soil and lake water, respectively.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Li, Pingjing
AU  - Li P
AD  - Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of 
      Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
FAU - Hu, Bin
AU  - Hu B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110527
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Arsenicals)
RN  - 0 (Water Pollutants, Chemical)
RN  - 451W47IQ8X (Sodium Chloride)
SB  - IM
MH  - Animal Feed/analysis
MH  - Animals
MH  - Arsenicals/*analysis
MH  - Chemical Fractionation/*methods
MH  - Electrophoresis, Capillary/*methods
MH  - Fresh Water/chemistry
MH  - Hydrogen-Ion Concentration
MH  - Sensitivity and Specificity
MH  - Sodium Chloride
MH  - Spectrophotometry, Ultraviolet/*methods
MH  - Swine
MH  - Water Pollutants, Chemical/analysis
EDAT- 2011/06/21 06:00
MHDA- 2011/09/21 06:00
CRDT- 2011/06/21 06:00
PHST- 2011/01/18 00:00 [received]
PHST- 2011/05/13 00:00 [revised]
PHST- 2011/05/17 00:00 [accepted]
PHST- 2011/06/21 06:00 [entrez]
PHST- 2011/06/21 06:00 [pubmed]
PHST- 2011/09/21 06:00 [medline]
AID - S0021-9673(11)00719-9 [pii]
AID - 10.1016/j.chroma.2011.05.058 [doi]
PST - ppublish
SO  - J Chromatogr A. 2011 Jul 22;1218(29):4779-87. doi: 10.1016/j.chroma.2011.05.058. 
      Epub 2011 May 27.