PMID- 21688005 OWN - NLM STAT- MEDLINE DCOM- 20120123 LR - 20211020 IS - 1432-1084 (Electronic) IS - 0938-7994 (Linking) VI - 21 IP - 11 DP - 2011 Nov TI - Identification and further differentiation of subendocardial and transmural myocardial infarction by fast strain-encoded (SENC) magnetic resonance imaging at 3.0 Tesla. PG - 2362-8 LID - 10.1007/s00330-011-2177-4 [doi] AB - OBJECTIVES: To investigate whether subendocardial and transmural myocardial infarction can be identified and differentiated using the peak circumferential and longitudinal strains measured by fast strain-encoded (SENC). METHODS: Nineteen patients with ischemic heart diseases underwent imaging with fast SENC and late gadolinium enhancement (LGE) MRI at 3 T. Fast SENC measurements were performed in three short-axis slices (basal, mid-ventricular and apical levels) and one long-axis view (four-chamber) to assess peak longitudinal and circumferential systolic strains. RESULTS: All patients showed myocardial infarction with an average of 7 positive LGE segments. A total of 304 segments for longitudinal strains (LS) and 114 segments for circumferential strains (CS) could be analysed. Positive LGE segments showed lower peak CS and LS compared with the no LGE segments (P < 0.0001 for both). Segments with subendocardial infarction showed reduced CS and LS compared with the no LGE segments (P < 0.0001 for both). There was a significant difference in CS between subendocardial and transmural infarct segments (P = 0.03), but no significant difference in LS between them (P = 0.64). CONCLUSIONS: Fast SENC can identify old myocardial infarction and differentiate subendocardial from transmural infarction. FAU - Oyama-Manabe, Noriko AU - Oyama-Manabe N AD - Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Kita15, Nishi 7, kita-ku, Sapporo, Japan. norikooyama@med.hokudai.ac.jp FAU - Ishimori, Naoki AU - Ishimori N FAU - Sugimori, Hiroyuki AU - Sugimori H FAU - Van Cauteren, Marc AU - Van Cauteren M FAU - Kudo, Kohsuke AU - Kudo K FAU - Manabe, Osamu AU - Manabe O FAU - Okuaki, Tomoyuki AU - Okuaki T FAU - Kamishima, Tamotsu AU - Kamishima T FAU - Ito, Yoichi M AU - Ito YM FAU - Tsutsui, Hiroyuki AU - Tsutsui H FAU - Tha, Khin Khin AU - Tha KK FAU - Terae, Satoshi AU - Terae S FAU - Shirato, Hiroki AU - Shirato H LA - eng PT - Journal Article DEP - 20110618 PL - Germany TA - Eur Radiol JT - European radiology JID - 9114774 RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Area Under Curve MH - Diagnosis, Differential MH - Diagnostic Imaging/methods MH - Female MH - Fibrosis MH - Gadolinium/*pharmacology MH - Humans MH - Magnetic Resonance Imaging/*methods MH - Male MH - Medical Oncology/*methods MH - Middle Aged MH - Myocardial Infarction/*diagnosis/*physiopathology MH - Sensitivity and Specificity EDAT- 2011/06/21 06:00 MHDA- 2012/01/24 06:00 CRDT- 2011/06/21 06:00 PHST- 2011/03/18 00:00 [received] PHST- 2011/05/21 00:00 [accepted] PHST- 2011/05/01 00:00 [revised] PHST- 2011/06/21 06:00 [entrez] PHST- 2011/06/21 06:00 [pubmed] PHST- 2012/01/24 06:00 [medline] AID - 10.1007/s00330-011-2177-4 [doi] PST - ppublish SO - Eur Radiol. 2011 Nov;21(11):2362-8. doi: 10.1007/s00330-011-2177-4. Epub 2011 Jun 18.