PMID- 2170004 OWN - NLM STAT- MEDLINE DCOM- 19901115 LR - 20201209 IS - 0304-3835 (Print) IS - 0304-3835 (Linking) VI - 53 IP - 2-3 DP - 1990 Sep TI - Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. PG - 97-102 AB - Therapeutic effects were obtained after systemic treatment of athymic mice bearing an epidermoid non-small cell human lung carcinoma (NSCLC) xenograft with tricyclodecan-9-yl xanthogenate (D609) and the potassium salt of a fatty (dodecanoic) acid. Extensive intratumoral necrosis was observed 3 days after the treatment. FAU - Sauer, G AU - Sauer G AD - Institute for Virus Research, German Cancer Research Center, Heidelberg. FAU - Amtmann, E AU - Amtmann E FAU - Hofmann, W AU - Hofmann W LA - eng PT - Journal Article PL - Ireland TA - Cancer Lett JT - Cancer letters JID - 7600053 RN - 0 (Antineoplastic Agents) RN - 0 (Bridged-Ring Compounds) RN - 0 (Drug Combinations) RN - 0 (Lauric Acids) RN - 0 (Norbornanes) RN - 0 (Thiocarbamates) RN - 0 (Thiones) RN - 1160N9NU9U (lauric acid) RN - 5QC1Z07M77 (tricyclodecane-9-yl-xanthogenate) SB - IM MH - Animals MH - *Antineoplastic Agents MH - Bridged-Ring Compounds/*therapeutic use MH - Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology MH - Drug Combinations MH - Humans MH - Lauric Acids/administration & dosage/*therapeutic use MH - Lung Neoplasms/*drug therapy/pathology MH - Mice MH - Mice, Nude MH - Necrosis MH - Neoplasm Transplantation MH - Norbornanes MH - Thiocarbamates MH - Thiones/*therapeutic use EDAT- 1990/09/01 00:00 MHDA- 1990/09/01 00:01 CRDT- 1990/09/01 00:00 PHST- 1990/09/01 00:00 [pubmed] PHST- 1990/09/01 00:01 [medline] PHST- 1990/09/01 00:00 [entrez] AID - 0304-3835(90)90200-H [pii] AID - 10.1016/0304-3835(90)90200-h [doi] PST - ppublish SO - Cancer Lett. 1990 Sep;53(2-3):97-102. doi: 10.1016/0304-3835(90)90200-h.