PMID- 21716678 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20230502 IS - 1741-4288 (Electronic) IS - 1741-427X (Print) IS - 1741-427X (Linking) VI - 2012 DP - 2012 TI - Effects of encapsulated propolis on blood glycemic control, lipid metabolism, and insulin resistance in type 2 diabetes mellitus rats. PG - 981896 LID - 10.1155/2012/981896 [doi] LID - 981896 AB - The present study investigates the encapsulated propolis on blood glycemic control, lipid metabolism, and insulin resistance in type 2 diabetes mellitus (T2DM) rats. The animal characteristics and biological assays of body weight, fasting blood glucose (FBG), fasting serum insulin (FINS), insulin act index (IAI), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured and euglycemic hyperinsulinemic glucose clamp technique were used to determine these effects. Our findings show that oral administration of encapsulated propolis can significantly inhibit the increasing of FBG and TG in T2DM rats and can improve IAI and M value in euglycemic hyperinsulinemic clamp experiment. There was no significant effects on body weight, TC, HDL-C, and LDL-C in T2DM rats treated with encapsulated propolis. In conclusion, the results indicate that encapsulated propolis can control blood glucose, modulate lipid metabolism, and improve the insulin sensitivity in T2DM rats. FAU - Li, Yajing AU - Li Y AD - College of Animal Science, Zhejiang University, No. 268 Kaixuan Road, Hangzhou 310029, China. FAU - Chen, Minli AU - Chen M FAU - Xuan, Hongzhuan AU - Xuan H FAU - Hu, Fuliang AU - Hu F LA - eng PT - Journal Article DEP - 20110612 PL - United States TA - Evid Based Complement Alternat Med JT - Evidence-based complementary and alternative medicine : eCAM JID - 101215021 PMC - PMC3118452 EDAT- 2011/07/01 06:00 MHDA- 2011/07/01 06:01 PMCR- 2011/06/12 CRDT- 2011/07/01 06:00 PHST- 2010/12/18 00:00 [received] PHST- 2011/03/15 00:00 [revised] PHST- 2011/04/13 00:00 [accepted] PHST- 2011/07/01 06:00 [entrez] PHST- 2011/07/01 06:00 [pubmed] PHST- 2011/07/01 06:01 [medline] PHST- 2011/06/12 00:00 [pmc-release] AID - 10.1155/2012/981896 [doi] PST - ppublish SO - Evid Based Complement Alternat Med. 2012;2012:981896. doi: 10.1155/2012/981896. Epub 2011 Jun 12.