PMID- 21716796
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20240314
IS  - 2589-0565 (Electronic)
IS  - 2589-0557 (Print)
IS  - 2589-0557 (Linking)
VI  - 31
IP  - 2
DP  - 2010 Jul
TI  - Pattern of sexually transmitted infections and performance of syndromic 
      management against etiological diagnosis in patients attending the sexually 
      transmitted infection clinic of a tertiary care hospital.
PG  - 104-8
LID - 10.4103/0253-7184.74998 [doi]
AB  - BACKGROUND AND OBJECTIVES: The availability of baseline information on the 
      epidemiology of sexually transmitted infections (STIs) and other associated risk 
      behaviors is essential for designing, implementing, and monitoring successful 
      targeted interventions. Also, continuous analysis of risk assessment and 
      prevalence-based screening studies are necessary to evaluate and monitor the 
      performance of syndromic management. The aim of the present study was to document 
      the pattern of common STIs and to evaluate the performance of syndromic case 
      management against their laboratory diagnoses. MATERIALS AND METHODS: Three 
      hundred consecutive patients who attended the STI clinic of a tertiary care 
      hospital at Delhi, with one or more of the complaints as enunciated by WHO in its 
      syndromic approach for the diagnosis of STIs, were included as subjects. Detailed 
      history, demographical data, and clinical features were recorded and screened for 
      common STIs by standard microbiological methods. RESULTS: The mean age was 24 
      years and most of the male patients were promiscuous and had contact with 
      commercial sex workers (CSWs 63.9%). Majority came with the complaint of genital 
      discharge (63 males; 54 females) followed by genital ulcer (61 males; 30 
      females). Genital herpes accounted for the maximum number of STI (86/300) 
      followed by syphilis (71/300). The sensitivity of genital discharge syndrome 
      (GDS) was high for Neisseria gonorrhoeae and Chlamydia trachomatis (96% and 91%, 
      respectively) while specificity was low (76% and 72%, respectively). The 
      sensitivity of genital ulcer syndrome for herpes simplex virus-2 (HSV-2) and 
      Treponema pallidum was 82.65% and 81.2%, respectively, while specificity reached 
      99% approximately. CONCLUSIONS: Viral STIs constitute the major burden of the STI 
      clinic and enhance the susceptibility of an individual to acquire or transmit HIV 
      through sexual contact. Syndromic algorithms have some shortcomings, and they 
      need to be periodically reviewed and adapted to the epidemiological patterns of 
      STI in a given setting.
FAU - Choudhry, Shilpee
AU  - Choudhry S
AD  - Department of Microbiology, UCMS & GTB Hospital, Dilshad Garden, Delhi, India.
FAU - Ramachandran, V G
AU  - Ramachandran VG
FAU - Das, Shukla
AU  - Das S
FAU - Bhattacharya, S N
AU  - Bhattacharya SN
FAU - Mogha, Narendra Singh
AU  - Mogha NS
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Sex Transm Dis AIDS
JT  - Indian journal of sexually transmitted diseases and AIDS
JID - 101730896
PMC - PMC3122595
OTO - NOTNLM
OT  - Genital discharge syndrome
OT  - HIV
OT  - genital ulcer syndrome
OT  - genital wart
OT  - sexually transmitted infection
OT  - syndromic approach
COIS- Conflict of Interest: None declared
EDAT- 2011/07/01 06:00
MHDA- 2011/07/01 06:01
PMCR- 2010/07/01
CRDT- 2011/07/01 06:00
PHST- 2011/07/01 06:00 [entrez]
PHST- 2011/07/01 06:00 [pubmed]
PHST- 2011/07/01 06:01 [medline]
PHST- 2010/07/01 00:00 [pmc-release]
AID - IJSTD-31-104 [pii]
AID - 10.4103/0253-7184.74998 [doi]
PST - ppublish
SO  - Indian J Sex Transm Dis AIDS. 2010 Jul;31(2):104-8. doi: 10.4103/0253-7184.74998.