PMID- 21717870
OWN - NLM
STAT- MEDLINE
DCOM- 20110719
LR  - 20221207
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 94 Suppl 2
DP  - 2011 Mar
TI  - Prevalence and risk factors of diabetic nephropathy among Thai patients with type 
      2 diabetes mellitus.
PG  - S1-5
AB  - BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end stage renal 
      disease. Clinically, DN is classified into 3 stages: microalbuminuria (MA), 
      macroalbuminuria and ESRD. The prevalence and risk factors of DN among patients 
      with type 2 diabetes mellitus (T2DM) in Thailand have not been well studied. 
      OBJECTIVE: To assess the prevalence of DN in patients with T2DM and to determine 
      their associated risk factors. MATERIAL AND METHOD: A cross-sectional study 
      evaluating 877 T2DM patients from the out-patient department of seven public 
      hospitals in Thailand was performed. Three random spot urine samples from all 
      patients were collected during 3 consecutive months. Normoalbuminuria, MA and 
      macroalbuminuria were defined as the presence of at least two out of three spot 
      urine tests for urine albumin/creatinine ratio showing less than 30, 30-300 and 
      more than 300 mg/gm respectively. RESULTS: Most patients were female, 60 years of 
      age or older, with BMI above 25 kg/m2, a family history of DM, uncontrolled blood 
      pressure, HbA1c above 7.0% and LDL above 100 mg/dl. The prevalence of 
      normoalbuminuria, MA and macroalbuminuria was 62.8, 26.0 and 11.2% respectively. 
      The prevalence of diabetic retinopathy in T2DM with normoalbuminuria, MA and 
      microalbuminuria was 18.5, 35.5 and 48.0% respectively. Associated risk factors 
      of DN were the duration of DM, HbA1c levels and uncontrolled hypertension. 
      CONCLUSION: The prevalence of all DN was 37.2%. Associated risk factors of DN 
      were the duration of DM, HbA1c levels and uncontrolled hypertension.
FAU - Krairittichai, Udom
AU  - Krairittichai U
AD  - Department of Medicine, College of Medicine, Rajavithi Hospital, Rangsit 
      University, Bangkok, Thailand. krairit@yahoo.com
FAU - Potisat, Somkiat
AU  - Potisat S
FAU - Jongsareejit, Amporn
AU  - Jongsareejit A
FAU - Sattaputh, Charnvate
AU  - Sattaputh C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Albuminuria
MH  - Asian People
MH  - Blood Glucose/metabolism
MH  - Blood Pressure
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*complications/diagnosis/epidemiology/physiopathology
MH  - Diabetic Nephropathies/complications/*epidemiology/etiology
MH  - Female
MH  - Glomerular Filtration Rate
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Hypertension/complications/epidemiology
MH  - Kidney Failure, Chronic/complications/*epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Thailand/epidemiology
EDAT- 2011/07/02 06:00
MHDA- 2011/07/20 06:00
CRDT- 2011/07/02 06:00
PHST- 2011/07/02 06:00 [entrez]
PHST- 2011/07/02 06:00 [pubmed]
PHST- 2011/07/20 06:00 [medline]
PST - ppublish
SO  - J Med Assoc Thai. 2011 Mar;94 Suppl 2:S1-5.