PMID- 21718609 OWN - NLM STAT- MEDLINE DCOM- 20130204 LR - 20110701 IS - 1000-503X (Print) IS - 1000-503X (Linking) VI - 33 IP - 3 DP - 2011 Jun TI - Effectiveness and safety of laparoscopic Roux-en-Y Gastric bypass in treating type 2 diabetes mellitus in non-morbidly obese patients. PG - 272-6 LID - 10.3881/j.issn.1000-503X.2011.03.013 [doi] AB - OBJECTIVE: To evaluate the effectiveness of laparoscopic Roux-en-Y gastric bypass (LRYGB) for achieving type 2 diabetes mellitus (T2DM) remission in patients with body mass index (BMI) in the range of 25-35 kg/m(2). METHODS: Twenty-two non-morbidly obese (BMI: 25-35 kg/m(2)) patients with T2DM underwent LRYGB. The changes of BMI, fasting plasma glucose (FPG), and glycosylated hemoglobin (HbA1c) levels were recorded, and the prognostic factors were analyzed. RESULTS: All these 22 patients successfully underwent LRYGB and were followed up for twelve months. Two patients (9.1%) developed complications: one patient had an early hemorrhage at the gastrojejunostomy site, and the other had frequent loose stools that required revision surgery. At 12 months, 14 patients (63.6%) showed T2DM remission, 6 (27.3%) showed glycemic control, and 2(9.1%) showed improvement. Compared with the latter two groups, patients in the T2DM remission group had significantly higher BMI (P=0.001), younger age (P=0.002), and shorter duration of diabetes (P=0.001) before operation. CONCLUSIONS: LYRGB can efficiently and safely treat T2DM in non-morbidly obese patients. Early intervention in these patients may yield better outcomes. FAU - Huang, Chih-kun AU - Huang CK AD - Bariatric & Metabolic International Surgery Center, International Minimally Invasive Surgery Training Center, E Da Hospital, Taiwan. dr.ckhuang@hotmail.com LA - eng PT - Journal Article PL - China TA - Zhongguo Yi Xue Ke Xue Yuan Xue Bao JT - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae JID - 8006230 SB - IM MH - Adult MH - Diabetes Mellitus, Type 2/complications/*surgery MH - Female MH - Gastric Bypass/*methods MH - Humans MH - Laparoscopy MH - Male MH - Middle Aged MH - Obesity/*complications MH - Prognosis MH - Treatment Outcome EDAT- 2011/07/02 06:00 MHDA- 2013/02/05 06:00 CRDT- 2011/07/02 06:00 PHST- 2011/07/02 06:00 [entrez] PHST- 2011/07/02 06:00 [pubmed] PHST- 2013/02/05 06:00 [medline] AID - 10.3881/j.issn.1000-503X.2011.03.013 [doi] PST - ppublish SO - Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Jun;33(3):272-6. doi: 10.3881/j.issn.1000-503X.2011.03.013.