PMID- 21719901
OWN - NLM
STAT- MEDLINE
DCOM- 20110726
LR  - 20191112
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 21
IP  - 3
DP  - 2011 Jun
TI  - Effects of immediate postexercise carbohydrate ingestion with and without protein 
      on neutrophil degranulation.
PG  - 205-13
AB  - The purpose of the study was to determine the effects of carbohydrate (CHO) 
      intake, with and without protein (PRO), immediately after prolonged strenuous 
      exercise on circulating bacterially stimulated neutrophil degranulation. Twelve 
      male runners completed 3 feeding interventions, 1 week apart, in randomized order 
      after 2 hr of running at 75% VO2max. The feeding interventions included a placebo 
      solution, a CHO solution equal to 1.2 g CHO/kg body mass (BM), and a CHO-PRO 
      solution equal to 1.2 g CHO/kg BM and 0.4 g PRO/kg BM (CHO+PRO) immediately 
      postexercise. All solutions were flavor and water-volume equivalent (12 ml/kg 
      BM). Circulating leukocyte counts, bacterially stimulated neutrophil 
      degranulation, plasma insulin, and cortisol were determined from blood samples 
      collected preexercise, immediately postexercise, and every 30 min until 180 min 
      postexercise. The immediate postexercise circulating leukocytosis, neutrophilia, 
      and lymphocytosis (p < .01 vs. preexercise) and the delayed lymphopenia (90 min 
      postexercise, p < .05 vs. preexercise) were similar on all trials. Bacterially 
      stimulated neutrophil degranulation decreased during recovery in control (23% at 
      180 min, p < .01 vs. preexercise) but remained above preexercise levels with CHO 
      and CHO+PRO. In conclusion, CHO ingestion, with or without PRO, immediately after 
      prolonged strenuous exercise prevented the decrease in bacterially stimulated 
      neutrophil degranulation during recovery.
FAU - Costa R, J S
AU  - Costa R JS
AD  - Extremes Research Group, Bangor University, Bangor, UK.
FAU - Walters, Robert
AU  - Walters R
FAU - Bilzon J, L J
AU  - Bilzon J LJ
FAU - Walsh, Neil P
AU  - Walsh NP
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Insulin)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Cell Degranulation/*physiology
MH  - Dietary Carbohydrates/*administration & dosage/*blood
MH  - Dietary Proteins/*administration & dosage/blood
MH  - Exercise/*physiology
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Insulin/blood
MH  - Male
MH  - Neutrophils/*physiology
MH  - Physical Endurance
MH  - Reference Values
MH  - Running
EDAT- 2011/07/02 06:00
MHDA- 2011/07/27 06:00
CRDT- 2011/07/02 06:00
PHST- 2011/07/02 06:00 [entrez]
PHST- 2011/07/02 06:00 [pubmed]
PHST- 2011/07/27 06:00 [medline]
AID - 10.1123/ijsnem.21.3.205 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2011 Jun;21(3):205-13. doi: 
      10.1123/ijsnem.21.3.205.