PMID- 21720119
OWN - NLM
STAT- MEDLINE
DCOM- 20111125
LR  - 20191112
IS  - 1882-1006 (Electronic)
IS  - 0015-6426 (Linking)
VI  - 52
IP  - 3
DP  - 2011
TI  - Determination of carbendazim, thiophanate, thiophanate-methyl and benomyl 
      residues in agricultural products by liquid chromatography-tandem mass 
      spectrometry.
PG  - 148-55
AB  - A simple and reliable liquid chromatographic-tandem mass spectrometric (LC-MS/MS) 
      method was developed for carbendazim (MBC), thiophanate (TE), thiophanate-methyl 
      (TM) and benomyl (BM) in agricultural products. These compounds were extracted 
      from agricultural products with methanol after addition of sodium L-ascorbate. BM 
      was hydrolyzed to MBC during the extraction with methanol. TE and TM were 
      cyclized to ethyl 2-benzimidazole carbamate (EBC) and MBC by refluxing at 120  degrees C 
      for 30 min with copper acetate in 50% acetic acid. MBC and EBC were cleaned up by 
      an n-hexane wash and extraction with ethyl acetate and determined by LC-MS/MS. 
      The mean recoveries from 10 agricultural products were in the range of 
      75.8-100.0%, and the relative standard deviations of 5 experiments were in the 
      range of 1.5-9.2% at concentrations equal to the maximum residue limits (MRLs). 
      The calibration curves were made by using commercial MBC and EBC as reference 
      analytical standards without refluxing. The quantification limits were 0.01 mg/kg 
      (as MBC), which is the uniform limit in the positive list system for agricultural 
      chemical residues in foods in Japan.
FAU - Nakamura, Munetomo
AU  - Nakamura M
AD  - Japan Food Research Laboratories, Nagayama,Tama-shi, Tokyo. nakamuram@jfrl.or.jp
FAU - Furumi, Yasuko
AU  - Furumi Y
FAU - Watanabe, Fumiko
AU  - Watanabe F
FAU - Mizukoshi, Kazushi
AU  - Mizukoshi K
FAU - Taniguchi, Makoto
AU  - Taniguchi M
FAU - Nemoto, Satoru
AU  - Nemoto S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Shokuhin Eiseigaku Zasshi
JT  - Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
JID - 0142214
RN  - 0 (Benzimidazoles)
RN  - 0 (Carbamates)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
RN  - 5Q0Y96D5I8 (Thiophanate)
RN  - H75J14AA89 (carbendazim)
RN  - TLW21058F5 (Benomyl)
SB  - IM
MH  - Benomyl/*analysis
MH  - Benzimidazoles/*analysis
MH  - Carbamates/*analysis
MH  - Chromatography, Liquid/*methods
MH  - Crops, Agricultural/*chemistry
MH  - Fungicides, Industrial/*analysis
MH  - Pesticide Residues/*analysis
MH  - Tandem Mass Spectrometry/*methods
MH  - Thiophanate/*analysis
EDAT- 2011/07/02 06:00
MHDA- 2011/12/13 00:00
CRDT- 2011/07/02 06:00
PHST- 2011/07/02 06:00 [entrez]
PHST- 2011/07/02 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
AID - JST.JSTAGE/shokueishi/52.148 [pii]
AID - 10.3358/shokueishi.52.148 [doi]
PST - ppublish
SO  - Shokuhin Eiseigaku Zasshi. 2011;52(3):148-55. doi: 10.3358/shokueishi.52.148.