PMID- 21729010
OWN - NLM
STAT- MEDLINE
DCOM- 20120112
LR  - 20110920
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 78
IP  - 4
DP  - 2011 Oct
TI  - Novel HLA class I and II alleles identified during routine registry typing in 
      2010.
PG  - 263-6
LID - 10.1111/j.1399-0039.2011.01728.x [doi]
AB  - Twenty-one novel human leukocyte antigen (HLA) class I and class II alleles are 
      described: seven HLA-A alleles, five HLA-C alleles, five HLA-B alleles and four 
      HLA-DRB1 alleles. Seventeen ( approximately 81%) of the 21 novel alleles are single nucleotide 
      substitution variants when compared with their most homologous allele. Nine of 
      these single nucleotide variants cause an amino acid substitution, while eight 
      are silent substitutions. The remaining novel alleles differ from their most 
      similar allele by two to three nucleotide substitutions. One novel HLA-C locus 
      allele encodes an amino acid change at codon 10 that previously has not been 
      reported to be polymorphic for this locus. Some of the new alleles encode novel 
      codons and unique amino acid changes at polymorphic positions in the HLA-A 
      (codons 24 and 156) and HLA-B (codons 40 and 115) loci.
CI  - (c) 2011 John Wiley & Sons A/S.
FAU - Lazaro, A M
AU  - Lazaro AM
AD  - Department of Pediatrics, Georgetown University Medical Center, Washington, DC 
      20057, USA.
FAU - Xiao, Y
AU  - Xiao Y
FAU - Masaberg, C
AU  - Masaberg C
FAU - Hwang, W Y K
AU  - Hwang WY
FAU - Yeoh, A E J
AU  - Yeoh AE
FAU - Weiyan, Y
AU  - Weiyan Y
FAU - Ng, J
AU  - Ng J
FAU - Hurley, C K
AU  - Hurley CK
FAU - Posch, P E
AU  - Posch PE
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20110705
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - *Alleles
MH  - Amino Acid Substitution
MH  - Female
MH  - Genetic Loci/physiology
MH  - HLA-A Antigens/*genetics
MH  - HLA-B Antigens/*genetics
MH  - HLA-C Antigens/*genetics
MH  - HLA-DRB1 Chains/*genetics
MH  - Histocompatibility Testing/methods
MH  - Humans
MH  - Male
MH  - Mutation, Missense
MH  - *Registries
EDAT- 2011/07/07 06:00
MHDA- 2012/01/13 06:00
CRDT- 2011/07/07 06:00
PHST- 2011/07/07 06:00 [entrez]
PHST- 2011/07/07 06:00 [pubmed]
PHST- 2012/01/13 06:00 [medline]
AID - 10.1111/j.1399-0039.2011.01728.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2011 Oct;78(4):263-6. doi: 10.1111/j.1399-0039.2011.01728.x. 
      Epub 2011 Jul 5.