PMID- 21730479
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110706
IS  - 0957-4484 (Print)
IS  - 0957-4484 (Linking)
VI  - 18
IP  - 46
DP  - 2007 Nov 21
TI  - Electrochemical impedance measurement of prostate cancer cells using carbon 
      nanotube array electrodes in a microfluidic channel.
PG  - 465505
LID - 10.1088/0957-4484/18/46/465505 [doi]
AB  - Highly aligned multi-wall carbon nanotubes were synthesized in the shape of 
      towers and embedded into fluidic channels as electrodes for impedance measurement 
      of LNCaP human prostate cancer cells. Tower electrodes up to 8 mm high were grown 
      and easily peeled off a silicon substrate. The nanotube electrodes were then 
      successfully soldered onto patterned printed circuit boards and cast into epoxy 
      under pressure. After polishing the top of the tower electrodes, RF plasma was 
      used to enhance the electrocatalytic effect by removing excess epoxy and 
      activating the open end of the nanotubes. Electrodeposition of Au particles on 
      the plasma-treated tower electrodes was done at a controlled density. Finally, 
      the nanotube electrodes were embedded into a polydimethylsiloxane (PDMS) channel 
      and electrochemical impedance spectroscopy was carried out with different 
      conditions. Preliminary electrochemical impedance spectroscopy results using 
      deionized water, buffer solution, and LNCaP prostate cancer cells showed that 
      nanotube electrodes can distinguish the different solutions and could be used in 
      future cell-based biosensor development.
FAU - Yun, Yeoheung
AU  - Yun Y
AD  - Smart Materials Nanotechnology Laboratory, Department of Mechanical Engineering, 
      University of Cincinnati, Cincinnati, OH 45221, USA.
FAU - Dong, Zhongyun
AU  - Dong Z
FAU - Shanov, Vesselin N
AU  - Shanov VN
FAU - Schulz, Mark J
AU  - Schulz MJ
LA  - eng
PT  - Journal Article
DEP - 20071012
PL  - England
TA  - Nanotechnology
JT  - Nanotechnology
JID - 101241272
EDAT- 2007/11/21 00:00
MHDA- 2007/11/21 00:01
CRDT- 2011/07/07 06:00
PHST- 2011/07/07 06:00 [entrez]
PHST- 2007/11/21 00:00 [pubmed]
PHST- 2007/11/21 00:01 [medline]
AID - S0957-4484(07)56134-9 [pii]
AID - 10.1088/0957-4484/18/46/465505 [doi]
PST - ppublish
SO  - Nanotechnology. 2007 Nov 21;18(46):465505. doi: 10.1088/0957-4484/18/46/465505. 
      Epub 2007 Oct 12.