PMID- 21730555 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20110706 IS - 0957-4484 (Print) IS - 0957-4484 (Linking) VI - 19 IP - 11 DP - 2008 Mar 19 TI - Type I collagen-templated assembly of silver nanoparticles and their application in surface-enhanced Raman scattering. PG - 115604 LID - 10.1088/0957-4484/19/11/115604 [doi] AB - Silver nanoparticles (Ag NPs) are one of the active substrates that are employed extensively in surface-enhanced Raman scattering (SERS), and aggregations of Ag NPs play an important role in enhancing the Raman signals. In this paper, we fabricated two kinds of SERS-active substrates utilizing the electrostatic adsorption and superior assembly properties of type I collagen. These were collagen-Ag NP aggregation films and nanoporous Ag films. Two probe molecules, 4-aminothiophenol (4-ATP) and methylene blue (MB), were studied on these substrates. These substrates showed reproducible SERS intensities with relative standard deviations (RSDs) of 8-10% and 11-14%, respectively, while the RSDs of the traditional thick Ag films were 12-28%. Also, the intensities for the 4-ATP spectrum on the collagen-templated nanoporous Ag film were approximately one order higher than those on the DNA-templated Ag film. FAU - Sun, Yujing AU - Sun Y AD - State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun 130022, People's Republic of China. FAU - Wei, Gang AU - Wei G FAU - Song, Yonghai AU - Song Y FAU - Wang, Li AU - Wang L FAU - Sun, Lanlan AU - Sun L FAU - Guo, Cunlan AU - Guo C FAU - Yang, Tao AU - Yang T FAU - Li, Zhuang AU - Li Z LA - eng PT - Journal Article DEP - 20080218 PL - England TA - Nanotechnology JT - Nanotechnology JID - 101241272 EDAT- 2008/03/19 00:00 MHDA- 2008/03/19 00:01 CRDT- 2011/07/07 06:00 PHST- 2011/07/07 06:00 [entrez] PHST- 2008/03/19 00:00 [pubmed] PHST- 2008/03/19 00:01 [medline] AID - S0957-4484(08)54099-2 [pii] AID - 10.1088/0957-4484/19/11/115604 [doi] PST - ppublish SO - Nanotechnology. 2008 Mar 19;19(11):115604. doi: 10.1088/0957-4484/19/11/115604. Epub 2008 Feb 18.