PMID- 2173765
OWN - NLM
STAT- MEDLINE
DCOM- 19901231
LR  - 20200724
IS  - 0022-538X (Print)
IS  - 1098-5514 (Electronic)
IS  - 0022-538X (Linking)
VI  - 64
IP  - 12
DP  - 1990 Dec
TI  - Characterization of the latency-related transcriptionally active region of the 
      bovine herpesvirus 1 genome.
PG  - 5730-7
AB  - Approximate 5' and 3' ends of the bovine herpesvirus 1 (BHV-1) latency-related 
      RNA (LR RNA) were mapped in rabbit trigeminal ganglia (TG) by in situ 
      hybridization. The data provide a size estimate of 0.77 to 1.16 kb for the LR 
      RNA. An LR RNA mapping to a similar location was also detected in TG of cattle 
      latently infected with BHV-1. The BHV-1 LR region is transcriptionally active in 
      bovine cell cultures lytically infected with BHV-1. A 1.15-kb transcript, present 
      at early and late times postinfection, of the same sense and approximate size 
      that seen in latently infected TG overlaps a 2.9-kb immediate-early and a 2.6-kb 
      early and late transcription unit present on the complementary strand. Sequence 
      analysis of the LR RNA sense strand indicates the presence of a potential 
      polymerase II promoter in close proximity to the 5' terminus of the LR RNA and 
      two open reading frames within its map positions. The complementary strand 
      contains the 3' portion of a large open reading frame that almost completely 
      overlaps the map position of the LR RNA present on the opposite strand.
FAU - Kutish, G
AU  - Kutish G
AD  - Department of Veterinary Science, University of Nebraska, Lincoln 68583.
FAU - Mainprize, T
AU  - Mainprize T
FAU - Rock, D
AU  - Rock D
LA  - eng
SI  - GENBANK/M61143
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - J Virol
JT  - Journal of virology
JID - 0113724
RN  - 0 (DNA, Viral)
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Cattle
MH  - Cells, Cultured
MH  - DNA, Viral/genetics
MH  - *Genes, Viral
MH  - Herpesvirus 1, Bovine/*genetics
MH  - Lung
MH  - Molecular Sequence Data
MH  - Open Reading Frames
MH  - RNA, Viral/genetics
MH  - Rabbits
MH  - Repetitive Sequences, Nucleic Acid
MH  - Restriction Mapping
MH  - *Transcription, Genetic
MH  - Turbinates
PMC - PMC248715
EDAT- 1990/12/01 00:00
MHDA- 1990/12/01 00:01
PMCR- 1990/12/01
CRDT- 1990/12/01 00:00
PHST- 1990/12/01 00:00 [pubmed]
PHST- 1990/12/01 00:01 [medline]
PHST- 1990/12/01 00:00 [entrez]
PHST- 1990/12/01 00:00 [pmc-release]
AID - 10.1128/JVI.64.12.5730-5737.1990 [doi]
PST - ppublish
SO  - J Virol. 1990 Dec;64(12):5730-7. doi: 10.1128/JVI.64.12.5730-5737.1990.