PMID- 21743214
OWN - NLM
STAT- MEDLINE
DCOM- 20110913
LR  - 20191210
IS  - 1319-2442 (Print)
IS  - 1319-2442 (Linking)
VI  - 22
IP  - 4
DP  - 2011 Jul
TI  - Artificial neural network for prediction of equilibrated dialysis dose without 
      intradialytic sample.
PG  - 705-11
AB  - Post-dialysis urea rebound (PDUR) is a cause of Kt/V overestimation when it is 
      calculated from pre-dialysis and the immediate post-dialysis blood urea 
      collections. Measuring PDUR requires a 30-or 60-min post-dialysis sampling, which 
      is inconvenient. In this study, a supervised neural network was proposed to 
      predict the equilibrated urea (C eq) at 60 min after the end of hemodialysis 
      (HD). Data of 150 patients from a dialysis unit were analyzed. C eq was measured 
      60 min after each HD session to calculate PDUR, equilibrated urea reduction rate 
      eq (URR), and ( eq Kt/V). The mean percentage of true urea rebound measured after 
      60 min of HD session was 19.6 +/- 10.7. The mean urea rebound observed from the 
      artificial neural network (ANN) was 18.6 +/- 13.9%, while the means were 24.8 +/- 
      14.1% and 21.3 +/- 3.49% using Smye and Daugirdas methods, respectively. The ANN 
      model achieved a correlation coefficient of 0.97 (P <0.0001), while the Smye and 
      Daugirdas methods yielded R = 0.81 and 0.93, respectively (P <0.0001); the errors 
      of the Smye method were larger than those of the other methods and resulted in a 
      considerable bias in all cases, while the predictive accuracy for ( eq Kt/V) 60 
      was equally good by the Daugirdas' formula and the ANN . We conclude that the use 
      of the ANN urea estimation yields accurate results when used to calculate ( eq 
      Kt/V).
FAU - Azar, Ahmad Taher
AU  - Azar AT
AD  - Electrical Communication & Electronics Systems Engineering department, Modern 
      Science and Arts University (MSA), 6th of October City, Egypt. 
      ahmad_t_azar@yahoo.com
FAU - Wahba, Khaled M
AU  - Wahba KM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Saudi Arabia
TA  - Saudi J Kidney Dis Transpl
JT  - Saudi journal of kidney diseases and transplantation : an official publication of 
      the Saudi Center for Organ Transplantation, Saudi Arabia
JID - 9436968
RN  - 8W8T17847W (Urea)
SB  - IM
MH  - Blood Urea Nitrogen
MH  - Humans
MH  - Kidney Failure, Chronic/blood/*therapy
MH  - Middle Aged
MH  - *Neural Networks, Computer
MH  - Predictive Value of Tests
MH  - Renal Dialysis/*standards
MH  - Urea/*blood
EDAT- 2011/07/12 06:00
MHDA- 2011/09/14 06:00
CRDT- 2011/07/12 06:00
PHST- 2011/07/12 06:00 [entrez]
PHST- 2011/07/12 06:00 [pubmed]
PHST- 2011/09/14 06:00 [medline]
AID - SaudiJKidneyDisTranspl_2011_22_4_705_82647 [pii]
PST - ppublish
SO  - Saudi J Kidney Dis Transpl. 2011 Jul;22(4):705-11.