PMID- 21744699
OWN - NLM
STAT- MEDLINE
DCOM- 20110728
LR  - 20191112
IS  - 0001-5385 (Print)
IS  - 0001-5385 (Linking)
VI  - 66
IP  - 3
DP  - 2011 Jun
TI  - Mitral annuloplasty for dilated cardiomyopathy with mitral regurgitation.
PG  - 303-7
AB  - OBJECTIVES: This study reports survival, functional status, the change in 
      post-operative left ventricular dimensions and function after'undersized mitral 
      annuloplasty' in patients with non-ischaemic non-valvular dilated cardiomyopathy 
      and secondary mitral regurgitation. PATIENTS AND METHODS: Between 2003 and 2009 
      10 patients (mean age 61.5 +/- 14 years) with non-ischaemic, non-valvular dilated 
      cardiomyopathy with left ventricular ejection fraction (LV EF) <40% (mean +/- SD, 
      30.7 +/- 5.27) underwent isolated mitral repair and annuloplasty. All patients 
      were receiving maximal drug therapy. Preoperatively 1 patient (10%) was 
      functioning in New York Heart Association (NYHA) class II, 8 patients (80%) in 
      class III and 1 patient (10%) in class IV. Transthoracic echocardiography was 
      performed immediately before surgery and one year after surgery to assess 
      valvular and ventricular function. For statistical analysis we have used paired 
      t-tests and Wilcoxon's rank test. RESULTS: There were no hospital deaths. 
      Duration of intubation and ICU stay was 1.8 +/- 1.3 and 3.8 +/- 1.8 days, 
      respectively. Functional class after one year was significantly better than the 
      preoperative value (from 3.00 +/- 0.47 to 1.40 +/- 0.52, P<0.001). One year 
      post-operative data showed significant improvement of LV EF (from 30.70 +/- 5.27 
      to 46.60 +/- 14.47%) and a decrease of the left ventricular diastolic dimension 
      (LVDd) (from 59.30 +/- 5.62 to 50.70 +/- 6.04 mm). CONCLUSION: Isolated 
      undersized mitral annuloplasty in patients with non-ischaemic non-valvular 
      dilated cardiomyopathy with associated mitral regurgitation, is a safe method 
      with the potential of improving functional class, LV EF, and LVDd after one year.
FAU - Sarens, Tom
AU  - Sarens T
AD  - Department of Intensive Care, University Hospitals Leuven, Leuven, Belgium. 
      tomsarens@hotmail.com
FAU - Herijgers, Paul
AU  - Herijgers P
FAU - Hermans, Hadewich
AU  - Hermans H
FAU - Herregods, Marie-Christine
AU  - Herregods MC
LA  - eng
PT  - Journal Article
PL  - England
TA  - Acta Cardiol
JT  - Acta cardiologica
JID - 0370570
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cardiac Valve Annuloplasty
MH  - Cardiomyopathy, Dilated/diagnostic imaging/epidemiology/mortality/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/*surgery
MH  - Mitral Valve Insufficiency/epidemiology
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - Ultrasonography
EDAT- 2011/07/13 06:00
MHDA- 2011/07/29 06:00
CRDT- 2011/07/13 06:00
PHST- 2011/07/13 06:00 [entrez]
PHST- 2011/07/13 06:00 [pubmed]
PHST- 2011/07/29 06:00 [medline]
AID - 10.1080/ac.66.3.2114129 [doi]
PST - ppublish
SO  - Acta Cardiol. 2011 Jun;66(3):303-7. doi: 10.1080/ac.66.3.2114129.