PMID- 21748859 OWN - NLM STAT- MEDLINE DCOM- 20111128 LR - 20191210 IS - 1942-7611 (Electronic) IS - 1942-7603 (Linking) VI - 3 IP - 7-8 DP - 2011 Jul-Aug TI - Aminoindanes--the next wave of 'legal highs'? PG - 479-82 LID - 10.1002/dta.318 [doi] AB - Due to its closed ring system, 2-aminoindane is a conformationally rigid analogue of amphetamine. Internet websites offering synthetic compounds as 'research chemicals' have recently been advertising 5,6-methylenedioxy-2-aminoindane (MDAI), 5, 6-methylenedioxy-N-methyl-2-aminoindane (MDMAI), 5-iodo-2-aminoindane (5-IAI), and 5-methoxy-6-methyl-2-aminoindane (MMAI). The chemistry, pharmacology, and toxicological aspects of this new class of psychoactive substances are reviewed, as these could become the next wave of 'legal highs'. CI - Copyright (c) 2011 John Wiley & Sons, Ltd. FAU - Sainsbury, P D AU - Sainsbury PD AD - Department of Forensic Science and Drug Monitoring, Franklin-Wilkins Building, King's College London SE1 9 NH, UK. FAU - Kicman, A T AU - Kicman AT FAU - Archer, R P AU - Archer RP FAU - King, L A AU - King LA FAU - Braithwaite, R A AU - Braithwaite RA LA - eng PT - Journal Article PT - Review DEP - 20110711 PL - England TA - Drug Test Anal JT - Drug testing and analysis JID - 101483449 RN - 0 (Amines) RN - 0 (Illicit Drugs) RN - 0 (Indans) RN - 0 (Neurotransmitter Agents) SB - IM MH - Amines/chemical synthesis/chemistry/pharmacology MH - Animals MH - Humans MH - Illicit Drugs/chemical synthesis/*chemistry/*pharmacology MH - Indans/chemical synthesis/*chemistry/*pharmacology MH - Neurotransmitter Agents/chemical synthesis/*chemistry/*pharmacology EDAT- 2011/07/13 06:00 MHDA- 2011/12/13 00:00 CRDT- 2011/07/13 06:00 PHST- 2011/05/23 00:00 [received] PHST- 2011/05/24 00:00 [revised] PHST- 2011/07/13 06:00 [entrez] PHST- 2011/07/13 06:00 [pubmed] PHST- 2011/12/13 00:00 [medline] AID - 10.1002/dta.318 [doi] PST - ppublish SO - Drug Test Anal. 2011 Jul-Aug;3(7-8):479-82. doi: 10.1002/dta.318. Epub 2011 Jul 11.