PMID- 21751552 OWN - NLM STAT- MEDLINE DCOM- 20111213 LR - 20191210 IS - 1426-9686 (Print) IS - 1426-9686 (Linking) VI - 30 IP - 180 DP - 2011 Jun TI - [Intravenous immunoglobulin therapy for kidney diseases in children]. PG - 423-6 AB - Intravenous immunoglobulin (IVIG) for the treatment of primary immunodeficiency disorders have been administrated for more than 25 years. However, the recognition of the anti-inflammatory and immune-modulatory actions of IVIG resulted broader applications to autoimmunity and systemic inflammatory conditions. The major focus of this review is the usefulness of IVIG therapy in children kidney disease, particularly in severe, atypical hemolytic-uremic syndrome and thrombotic thrombocytopenic purpura, refractory to standard therapy, including plasmaferesis. The role of intravenous immunoglobulins in the treatment and prevention of infection, the most common complication in nephrotic syndrome is also discussed. Probably, in the future, similarly to adults, IVIG will be used for the therapy of some forms of glomerulopathies. FAU - Zwolinska, Danuta AU - Zwolinska D AD - Akademia Medyczna we Wroclawiu, Katedra i Klinika Nefrologii Pediatrycznej. zwolin@nefped.am.wroc.pl LA - pol PT - Journal Article PT - Review TT - Terapia dozylnymi preparatami immunoglobulin w chorobach nerek u dzieci. PL - Poland TA - Pol Merkur Lekarski JT - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JID - 9705469 RN - 0 (Anti-Inflammatory Agents) RN - 0 (Immunoglobulins, Intravenous) RN - 0 (Immunologic Factors) SB - IM MH - Anti-Inflammatory Agents/*administration & dosage MH - Child MH - Hemolytic-Uremic Syndrome/complications/*drug therapy/immunology MH - Humans MH - Immunization, Passive MH - Immunoglobulins, Intravenous/*administration & dosage MH - Immunologic Factors/*administration & dosage MH - Infection Control/methods MH - Infections/etiology MH - Nephrotic Syndrome/complications/*drug therapy/immunology MH - Purpura, Thrombotic Thrombocytopenic/complications/*drug therapy/immunology EDAT- 2011/07/15 06:00 MHDA- 2011/12/14 06:00 CRDT- 2011/07/15 06:00 PHST- 2011/07/15 06:00 [entrez] PHST- 2011/07/15 06:00 [pubmed] PHST- 2011/12/14 06:00 [medline] PST - ppublish SO - Pol Merkur Lekarski. 2011 Jun;30(180):423-6.