PMID- 21755035
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20231105
IS  - 2090-0392 (Electronic)
VI  - 2011
DP  - 2011
TI  - Resistant hypertension and obstructive sleep apnea in the primary-care setting.
PG  - 340929
LID - 10.4061/2011/340929 [doi]
AB  - We ascertained the prevalence of resistant hypertension (RH) among blacks and 
      determined whether RH patients are at greater risk for obstructive sleep apnea 
      (OSA) than hypertensives. Method. Data emanated from Metabolic Syndrome Outcome 
      Study (MetSO), a study investigating metabolic syndrome among blacks in the 
      primary-care setting. Sample of 200 patients (mean age = 63 +/- 13 years; female = 
      61%) with a diagnosis of hypertension provided subjective and clinical data. RH 
      was defined using the JNC 7and European Society guidelines. We assessed OSA risk 
      using the Apnea Risk Evaluation System ARES), defining high risk as a total ARES 
      score >/=6. Results. Overall, 26% met criteria for RH and 40% were at high OSA 
      risk. Logistic regression analysis, adjusting for effects of age, gender, and 
      medical co morbidities, showed that patients with RH were nearly 2.5 times more 
      likely to be at high OSA risk, relative to those with hypertension (OR = 2.46, 
      95% CI: 1.03-5.88, P < .05). Conclusion. Our findings show that the prevalence of 
      RH among blacks fell within the range of RH for the general hypertensive 
      population (3-29%). However, patients with RH were at significantly greater risk 
      of OSA compared to patients with hypertension.
FAU - Demede, M
AU  - Demede M
AD  - Brooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate 
      Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USA.
FAU - Pandey, A
AU  - Pandey A
FAU - Zizi, F
AU  - Zizi F
FAU - Bachmann, R
AU  - Bachmann R
FAU - Donat, M
AU  - Donat M
FAU - McFarlane, S I
AU  - McFarlane SI
FAU - Jean-Louis, G
AU  - Jean-Louis G
FAU - Ogedegbe, G
AU  - Ogedegbe G
LA  - eng
GR  - P20 MD005092/MD/NIMHD NIH HHS/United States
GR  - R01 MD004113/MD/NIMHD NIH HHS/United States
GR  - R25 HL105444/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20110608
PL  - United States
TA  - Int J Hypertens
JT  - International journal of hypertension
JID - 101538881
PMC - PMC3132606
EDAT- 2011/07/15 06:00
MHDA- 2011/07/15 06:01
CRDT- 2011/07/15 06:00
PHST- 2011/02/14 00:00 [received]
PHST- 2011/03/28 00:00 [accepted]
PHST- 2011/07/15 06:00 [entrez]
PHST- 2011/07/15 06:00 [pubmed]
PHST- 2011/07/15 06:01 [medline]
AID - 10.4061/2011/340929 [doi]
PST - ppublish
SO  - Int J Hypertens. 2011;2011:340929. doi: 10.4061/2011/340929. Epub 2011 Jun 8.