PMID- 2176781
OWN - NLM
STAT- MEDLINE
DCOM- 19910220
LR  - 20151119
IS  - 0004-1955 (Print)
IS  - 0004-1955 (Linking)
VI  - 52
IP  - 9
DP  - 1990
TI  - [Malignant triton tumor (immunomorphological research)].
PG  - 39-46
AB  - Immunohistochemical study with the use of PAP method on paraffine sections of two 
      cases of triton tumour one of which developed against the background of 
      Recklinghausen disease. The presence of vimentin and S-100 protein in the 
      neurofibromatous cells and spindle-cell component of malignant triton tumour is 
      shown. The muscle differentiation markers (desmin and myoglobin) are found in the 
      polymorph-cell component. The positive reaction of the cytoplasmic processes of 
      some cells in the neurofibromatous tissue to the antibodies against GFAP (glial 
      fibrillar acid protein) is discussed. It is suggested that the number of S-100 
      protein-positive and vimentine-positive cells in the peripheral nerve sheath 
      tumours reflects the degree of their differentiation. Hypotheses of the 
      histogenesis of these rare tumours are discussed. The panel of antibodies for the 
      differential diagnosis of malignant triton tumour with rhabdomyosarcoma, 
      malignant schwannoma and other soft tissue tumours is proposed.
FAU - Smirnov, A V
AU  - Smirnov AV
FAU - Povisil, C
AU  - Povisil C
LA  - rus
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Zlokachestvennaia triton-opukhol' (immunomorfologicheskoe issledovanie).
PL  - Russia (Federation)
TA  - Arkh Patol
JT  - Arkhiv patologii
JID - 0370604
RN  - 0 (Biomarkers, Tumor)
RN  - 0 (Desmin)
RN  - 0 (Myoglobin)
RN  - 0 (S100 Proteins)
RN  - 0 (Vimentin)
SB  - IM
MH  - Adolescent
MH  - Aged
MH  - Biomarkers, Tumor/metabolism
MH  - Desmin/metabolism
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Immunohistochemistry
MH  - Leg
MH  - Male
MH  - Myoglobin/metabolism
MH  - Neoplasms, Germ Cell and Embryonal/diagnosis/metabolism/*pathology
MH  - Neurilemmoma/diagnosis/metabolism/*pathology
MH  - Neurofibromatosis 1/diagnosis/metabolism/pathology
MH  - Rhabdomyosarcoma/diagnosis/metabolism/pathology
MH  - S100 Proteins/metabolism
MH  - Soft Tissue Neoplasms/diagnosis/metabolism/pathology
MH  - Thorax
MH  - Vimentin/metabolism
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
PST - ppublish
SO  - Arkh Patol. 1990;52(9):39-46.