PMID- 21767995 OWN - NLM STAT- MEDLINE DCOM- 20120127 LR - 20110909 IS - 1525-5069 (Electronic) IS - 1525-5050 (Linking) VI - 22 IP - 1 DP - 2011 Sep TI - Interictal discharges and cognition. PG - 134-6 LID - 10.1016/j.yebeh.2011.06.010 [doi] AB - In daily clinical practice, doctors are frequently confronted with the issue whether treatment is necessary when the patient is without (further) seizures, but nevertheless still shows interictal discharges on the EEG. Will these discharges influence cognition temporarily and in time correlated with the discharges or is there a longer-lasting or even cumulative impairment? Which children are most at risk and when? Based on available literature in this field and own research in patients with Benign Epilepsy with Centro-Temporal spikes (BECTS), an inventory has been made of all issues that has to be addressed to answer these crucial questions. Prospective studies in drug naive children with BECTS (with or without behavioral comorbidity) are highly recommended. CI - Copyright (c) 2011 Elsevier Inc. All rights reserved. FAU - Nicolai, Joost AU - Nicolai J AD - Neurology Department, Maastricht University Medical Center, The Netherlands. FAU - Kasteleijn-Nolst Trenite, Dorothee AU - Kasteleijn-Nolst Trenite D LA - eng PT - Journal Article PT - Review DEP - 20110720 PL - United States TA - Epilepsy Behav JT - Epilepsy & behavior : E&B JID - 100892858 SB - IM MH - Brain/physiopathology MH - Child MH - Cognition Disorders/*complications/diagnosis/physiopathology MH - Electroencephalography MH - Epilepsy, Rolandic/*complications/physiopathology MH - Humans EDAT- 2011/07/20 06:00 MHDA- 2012/01/28 06:00 CRDT- 2011/07/20 06:00 PHST- 2011/06/06 00:00 [received] PHST- 2011/06/11 00:00 [accepted] PHST- 2011/07/20 06:00 [entrez] PHST- 2011/07/20 06:00 [pubmed] PHST- 2012/01/28 06:00 [medline] AID - S1525-5050(11)00355-6 [pii] AID - 10.1016/j.yebeh.2011.06.010 [doi] PST - ppublish SO - Epilepsy Behav. 2011 Sep;22(1):134-6. doi: 10.1016/j.yebeh.2011.06.010. Epub 2011 Jul 20.