PMID- 21770246
OWN - NLM
STAT- MEDLINE
DCOM- 20120816
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 4
DP  - 2011 Apr
TI  - [Simultaneous determination of sulfonylurea herbicides in ginseng by ultra 
      performance liquid chromatography-tandem mass spectrometry].
PG  - 346-52
AB  - An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/ MS) 
      method was developed for the determination of the fifteen sulfonylurea herbicides 
      in ginseng. The pesticides were extracted with acetonitrile, cleaned-up by an 
      ENVI-Carbon solid phase extraction cartridge, eluted with 1% formic acid in 
      methanol-dichlormethane (20:80, v/v), separated with UPLC and detected with MS/MS 
      in multiple reaction monitoring (MRM) mode via positive electrospray ionization 
      (ESI+). The method was validated at three fortification levels in ginseng. The 
      validation results were as follows. The standard calibration curves for the 
      fifteen sulfonylurea herbicides all showed linear over the range of 2-100 
      microg/L with the correlation coefficients between 0.996 and 0.999. The average 
      recoveries of the fifteen sulfonylurea herbicides at the three fortification 
      levels of 5, 25 and 50 microg/kg were between 84.9% and 104.3% with the relative 
      standard deviations (RSDs) between 2.4% and 11.9%. The limit of quantification 
      (LOQ) was defined as the lowest concentration that could be measured with 
      acceptable precision and accuracy. The LOQs of all the fifteen sulfonylurea 
      herbicides in ginseng were 5 microg/kg. It was indicated that this method is 
      easier, more sensitive and has a better purification effect. The sensitivity, 
      accuracy and precision of the method were all acceptable. So, this method can be 
      further applied to investigating the contamination status of traditional Chinese 
      medicine by the sulfonylurea herbicides
FAU - Li, Na
AU  - Li N
AD  - Central Laboratory of Tianjin Academy of Agricultural Sciences, Tianjin 300381, 
      China.
FAU - Li, Hui
AU  - Li H
FAU - Shao, Hui
AU  - Shao H
FAU - Liu, Lei
AU  - Liu L
FAU - Zhang, Yuting
AU  - Zhang Y
FAU - Guo, Yongze
AU  - Guo Y
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Herbicides)
RN  - 0 (Pesticide Residues)
RN  - 0 (Sulfonylurea Compounds)
SB  - IM
MH  - Chromatography, High Pressure Liquid/methods
MH  - *Drug Contamination
MH  - Herbicides/analysis
MH  - Panax/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Sulfonylurea Compounds/*analysis
MH  - Tandem Mass Spectrometry/methods
EDAT- 2011/07/21 06:00
MHDA- 2012/08/17 06:00
CRDT- 2011/07/21 06:00
PHST- 2011/07/21 06:00 [entrez]
PHST- 2011/07/21 06:00 [pubmed]
PHST- 2012/08/17 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.00346 [doi]
PST - ppublish
SO  - Se Pu. 2011 Apr;29(4):346-52. doi: 10.3724/sp.j.1123.2011.00346.