PMID- 21771744
OWN - NLM
STAT- MEDLINE
DCOM- 20120326
LR  - 20111021
IS  - 1468-2834 (Electronic)
IS  - 0002-0729 (Linking)
VI  - 40
IP  - 6
DP  - 2011 Nov
TI  - Predictors of in-hospital mortality of older patients admitted for 
      community-acquired pneumonia.
PG  - 736-41
LID - 10.1093/ageing/afr087 [doi]
AB  - BACKGROUND: there were a few studies on the case mortality of pneumonia in older 
      people, of which results were conflicting. OBJECTIVES: this study aimed to 
      identify risk factors associated with in-hospital mortality in older patients 
      admitted for community-acquired pneumonia (CAP). DESIGN: a prospective cohort 
      study. SETTING: hospital sample. SUBJECTS: during the 1-year study period (from 
      October 2009 to September 2010), 488 older patients aged 65 or above were 
      recruited. METHODS: demographic characteristics, medical illnesses (Charlson's 
      comorbidity index (CCI)), premorbid functional status (Katz's index) and baseline 
      blood tests were recorded. The outcome was in-hospital mortality. RESULTS: in 
      this cohort of patients, the mean age was 81.0 years (+/-7.9) and 282 (57.8%) were 
      male. Nursing home residents accounted for 23.8% (116/488) of study subjects. The 
      median CCI was 2 (inter-quartile range (IQR): 1-3); 60 (12.3%) patients succumbed 
      during hospital stay. Logistic regression showed that comorbidities, mid-arm 
      circumference, serum albumin level and severity of pneumonia (Confusion, blood 
      Urea nitrogen, Respiratory rate and low Blood pressure (CURB) score) were 
      independent predictors of in-hospital mortality of pneumonia. CONCLUSION: in 
      keeping with previous studies, CURB score and comorbidities were the most 
      significant independent predictors of mortality of CAP in older patients. Our 
      study concluded that nutritional status was also an important factor affecting 
      their survival. This study failed to demonstrate functional status as a predictor 
      of mortality due to limitation of Katz's index.
FAU - Ma, Hon Ming
AU  - Ma HM
AD  - Department of Medicine and Therapeutics, Prince of Wales Hospital, the Chinese 
      University of Hong Kong, China. hmma@cuhk.edu.hk
FAU - Tang, Wing Han
AU  - Tang WH
FAU - Woo, Jean
AU  - Woo J
LA  - eng
PT  - Journal Article
DEP - 20110718
PL  - England
TA  - Age Ageing
JT  - Age and ageing
JID - 0375655
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Urea Nitrogen
MH  - Cohort Studies
MH  - Community-Acquired Infections/diagnosis/*epidemiology/*mortality
MH  - Comorbidity
MH  - Confusion
MH  - Female
MH  - *Hospital Mortality
MH  - Humans
MH  - Hypotension
MH  - Logistic Models
MH  - Male
MH  - Pneumonia/diagnosis/*epidemiology/*mortality
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Prospective Studies
MH  - Respiratory Rate
MH  - Retrospective Studies
MH  - Risk Factors
EDAT- 2011/07/21 06:00
MHDA- 2012/03/27 06:00
CRDT- 2011/07/21 06:00
PHST- 2011/07/21 06:00 [entrez]
PHST- 2011/07/21 06:00 [pubmed]
PHST- 2012/03/27 06:00 [medline]
AID - afr087 [pii]
AID - 10.1093/ageing/afr087 [doi]
PST - ppublish
SO  - Age Ageing. 2011 Nov;40(6):736-41. doi: 10.1093/ageing/afr087. Epub 2011 Jul 18.