PMID- 21772868 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20111110 LR - 20211020 IS - 1735-1995 (Print) IS - 1735-7136 (Electronic) IS - 1735-1995 (Linking) VI - 14 IP - 2 DP - 2009 Mar TI - A risk score development for diabetic retinopathy screening in Isfahan-Iran. PG - 105-10 AB - BACKGROUND: The purpose of this study was to develop a simple risk score as screening tool for retinopathy in type II diabetic patients. METHODS: A cross-sectional study was carried out recruiting 3734 patients with type II diabetes in an outpatient clinic in Isfahan Endocrinology and Metabolism Research Center (IEMRC), Iran. The logistic regression was used as a model to predict diabetic retinopathy. The cut-off value for the risk score was determined using the Receiver Operating Characteristic (ROC) curve procedure. RESULTS: According to final models, being male, having lower body mass index (BMI), being older, longer duration of diabetes and higher HbA1c were correlated with increased risk of diabetic retinopathy. Area under the Curve (ROC) was 0.704 (95% CI: 0.685-0.723). A value >/= 52.5 had the optimum sensitivity (60%) and specificity (69%) for determining diabetic retinopathy. CONCLUSIONS: The results indicated that risk factors for retinopathy were sex, BMI, age, duration of diabetes and HbA1c levels. In conclusion, applying developed retinopathy risk score is a practical way to identify patients who are at high risk for developing diabetic retinopathy for an early treatment. FAU - Hosseini, Sayed Mohsen AU - Hosseini SM AD - Department of Epidemiology & Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Maracy, Mohammad Reza AU - Maracy MR FAU - Amini, Masoud AU - Amini M FAU - Baradaran, Hamid Reza AU - Baradaran HR LA - eng PT - Journal Article PL - India TA - J Res Med Sci JT - Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences JID - 101235599 PMC - PMC3129085 OTO - NOTNLM OT - Retinopathy risk score OT - receiver operating characteristic curve OT - sensitivity OT - specificity COIS- Conflict of Interest Authors have no conflicts of interest. EDAT- 2009/03/01 00:00 MHDA- 2009/03/01 00:01 PMCR- 2009/03/01 CRDT- 2011/07/21 06:00 PHST- 2008/09/19 00:00 [received] PHST- 2009/03/10 00:00 [accepted] PHST- 2011/07/21 06:00 [entrez] PHST- 2009/03/01 00:00 [pubmed] PHST- 2009/03/01 00:01 [medline] PHST- 2009/03/01 00:00 [pmc-release] AID - JRMS-14-105 [pii] PST - ppublish SO - J Res Med Sci. 2009 Mar;14(2):105-10.