PMID- 21773670
OWN - NLM
STAT- MEDLINE
DCOM- 20120301
LR  - 20211020
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
VI  - 21
IP  - 3
DP  - 2011 Sep
TI  - HIV/AIDS patients with HIV vasculopathy and VZV vasculitis: a case series.
PG  - 145-51
LID - 10.1007/s00062-011-0087-0 [doi]
AB  - PURPOSE: Stroke is a rising cause of mortality in human immunodeficiency virus 
      (HIV) and acquired immunodeficiency syndrome (AIDS) populations. The etiology of 
      stroke remains at the core of the decision-making process to treat and prevent 
      recurrent events. In this population HIV vasculopathy (HIV-V) and varicella 
      zoster virus (VZV) vasculitis are elusive causes of stroke. This study 
      investigated radiological markers that could help identify possible etiological 
      causes. METHODS: A series of nine consecutive patients seen at a large 
      metropolitan hospital who presented with AIDS and stroke with the suspicion of 
      either HIV vasculopathy (HIV-V) or VZV vasculitis (VZV-V) were included. A 
      standardized diagnostic approach was used to for HIV-V and VZV-V. Data on 
      frequencies and typical images are reported. RESULTS: Of the nine patients five 
      had VZV-V and four had HIV-V. Patients with VZV-V were generally younger than 
      those with HIV-V; however, no other significant demographic or cardiovascular 
      differences were found. Of the five patients with VZV-V four had small, deep, 
      subcortical ischemic strokes and only one in this group had a large, cortical, 
      hemispheric stroke but in the HIV-V group three patients had large, cortical 
      hemispheric strokes and only one patient had small, subcortical ischemic strokes. 
      CONCLUSIONS: In this series VZV-V seemed to present more often with deep-seated 
      ischemic infarcts, while HIV-V appeared to be associated with large, hemispheric 
      stroke. It seems plausible that this difference is related to the type of 
      arteries infected by each virus. These findings are preliminary and should be 
      confirmed with better studies.
FAU - Gutierrez, J
AU  - Gutierrez J
AD  - Department of Neurology, Miller School of Medicine, University of Miami, 1120 NW 
      14th Street, 33136, Miami, FL, USA.
FAU - Ortiz, G
AU  - Ortiz G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20110720
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
SB  - IM
MH  - AIDS Arteritis, Central Nervous System/*diagnosis
MH  - AIDS-Related Opportunistic Infections/*diagnosis
MH  - Adolescent
MH  - Adult
MH  - Angiography, Digital Subtraction
MH  - Cerebral Angiography
MH  - Cerebral Arteries/pathology
MH  - Cerebral Infarction/*diagnosis
MH  - Diagnosis, Differential
MH  - Encephalitis, Varicella Zoster/*diagnosis
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Magnetic Resonance Angiography/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Stroke/*diagnosis
MH  - Vasculitis/*diagnosis
MH  - Young Adult
EDAT- 2011/07/21 06:00
MHDA- 2012/03/02 06:00
CRDT- 2011/07/21 06:00
PHST- 2011/02/28 00:00 [received]
PHST- 2011/06/02 00:00 [accepted]
PHST- 2011/07/21 06:00 [entrez]
PHST- 2011/07/21 06:00 [pubmed]
PHST- 2012/03/02 06:00 [medline]
AID - 10.1007/s00062-011-0087-0 [doi]
PST - ppublish
SO  - Clin Neuroradiol. 2011 Sep;21(3):145-51. doi: 10.1007/s00062-011-0087-0. Epub 
      2011 Jul 20.