PMID- 2177778 OWN - NLM STAT- MEDLINE DCOM- 19910308 LR - 20190828 IS - 0146-6615 (Print) IS - 0146-6615 (Linking) VI - 32 IP - 3 DP - 1990 Nov TI - Detection of human herpesvirus 6 DNA in throat swabs by polymerase chain reaction. PG - 139-42 AB - The detection of human herpesvirus 6 (HHV-6) DNA was carried out in throat swabs of adults and children by the polymerase chain reaction, and isolation of virus was also attempted from peripheral mononuclear cells. Although virus was isolated only from peripheral blood mononuclear cells of infants with exanthem subitum, HHV-6 DNA was detected in one of 30 healthy adults (3%), two of nine adults (22%) with common cold, two of 10 infants (20%) with exanthem subitum, four of 39 febrile children (10%) with antibody to HHV-6 (including three of 10 infants aged under 1 year old, and one of 29 children aged over 1 year old). However, HHV-6 DNA was not detected in samples from healthy neonates. FAU - Kido, S AU - Kido S AD - Department of Virology, Osaka University, Japan. FAU - Kondo, K AU - Kondo K FAU - Kondo, T AU - Kondo T FAU - Morishima, T AU - Morishima T FAU - Takahashi, M AU - Takahashi M FAU - Yamanishi, K AU - Yamanishi K LA - eng PT - Journal Article PL - United States TA - J Med Virol JT - Journal of medical virology JID - 7705876 RN - 0 (DNA, Viral) SB - IM MH - Adult MH - Base Sequence MH - Common Cold/microbiology MH - DNA, Viral/*analysis/chemistry MH - Exanthema Subitum/microbiology MH - Herpesvirus 6, Human/genetics/*isolation & purification MH - Humans MH - Infant MH - Infant, Newborn MH - Leukocytes, Mononuclear/microbiology MH - Middle Aged MH - Molecular Sequence Data MH - Pharynx/*microbiology MH - Polymerase Chain Reaction EDAT- 1990/11/01 00:00 MHDA- 1990/11/01 00:01 CRDT- 1990/11/01 00:00 PHST- 1990/11/01 00:00 [pubmed] PHST- 1990/11/01 00:01 [medline] PHST- 1990/11/01 00:00 [entrez] AID - 10.1002/jmv.1890320302 [doi] PST - ppublish SO - J Med Virol. 1990 Nov;32(3):139-42. doi: 10.1002/jmv.1890320302.