PMID- 21777940 OWN - NLM STAT- MEDLINE DCOM- 20120222 LR - 20191210 IS - 1879-1298 (Electronic) IS - 0045-6535 (Linking) VI - 85 IP - 6 DP - 2011 Oct TI - Biotic and abiotic degradation of illicit drugs, their precursor, and by-products in soil. PG - 1002-9 LID - 10.1016/j.chemosphere.2011.06.102 [doi] AB - This study presents the first systematic information on the degradation patterns of clandestine drug laboratory chemicals in soil. The persistence of five compounds - parent drugs (methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA)), precursor (pseudoephedrine), and synthetic by-products N-formylmethylamphetamine and 1-benzyl-3-methylnaphthalene) - were investigated in laboratory scale for 1 year in three different South Australian soils both under non-sterile and sterile conditions. The results of the degradation study indicated that 1-benzyl-3-methylnaphthalene and methamphetamine persist for a long time in soil compared to MDMA and pseudoephedrine; N-formylmethylamphetamine exhibits intermediate persistence. The role of biotic versus abiotic soil processes on the degradation of target compounds was also varied significantly for different soils as well as with the progress in incubation period. The degradation of methamphetamine and 1-benzyl-3-methylnaphthalene can be considered as predominantly biotic as no measureable changes in concentrations were recorded in the sterile soils within a 1 year period. The results of the present work will help forensic and environmental scientists to precisely determine the environmental impact of chemicals associated with clandestine drug manufacturing laboratories. CI - Copyright (c) 2011 Elsevier Ltd. All rights reserved. FAU - Pal, Raktim AU - Pal R AD - Centre for Environmental Risk Assessment and Remediation, University of South Australia, Mawson Lakes, Adelaide, South Australia 5095, Australia. FAU - Megharaj, Mallavarapu AU - Megharaj M FAU - Kirkbride, K Paul AU - Kirkbride KP FAU - Heinrich, Tunde AU - Heinrich T FAU - Naidu, Ravi AU - Naidu R LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20110722 PL - England TA - Chemosphere JT - Chemosphere JID - 0320657 RN - 0 (Amphetamines) RN - 0 (Illicit Drugs) RN - 0 (Soil) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Amphetamines/chemistry/metabolism MH - *Environmental Pollution MH - Illicit Drugs/*chemistry/*metabolism MH - N-Methyl-3,4-methylenedioxyamphetamine/chemistry/metabolism MH - Soil/*chemistry EDAT- 2011/07/23 06:00 MHDA- 2012/02/23 06:00 CRDT- 2011/07/23 06:00 PHST- 2011/03/26 00:00 [received] PHST- 2011/06/23 00:00 [revised] PHST- 2011/06/26 00:00 [accepted] PHST- 2011/07/23 06:00 [entrez] PHST- 2011/07/23 06:00 [pubmed] PHST- 2012/02/23 06:00 [medline] AID - S0045-6535(11)00760-0 [pii] AID - 10.1016/j.chemosphere.2011.06.102 [doi] PST - ppublish SO - Chemosphere. 2011 Oct;85(6):1002-9. doi: 10.1016/j.chemosphere.2011.06.102. Epub 2011 Jul 22.