PMID- 21780028
OWN - NLM
STAT- MEDLINE
DCOM- 20110830
LR  - 20110722
IS  - 1211-264X (Print)
IS  - 1211-264X (Linking)
VI  - 17
IP  - 3
DP  - 2011 Jun
TI  - [Disseminated infection with Mycobacterium avium in a patient with newly 
      diagnosed HIV infection].
PG  - 92-5
AB  - In the Czech Republic, mycobacteriosis is relatively rare. The low incidence 
      probably reflects high BCG coverage rates in the Czech population. Globally, the 
      importance of BCG vaccine has been increasing, as a result of acquired 
      immunodeficiencies, particularly HIV infection. The presented case report 
      describes the course of disseminated mycobacteriosis in a Vietnamese asylum 
      seeker with newly diagnosed advanced HIV infection. In HIV patients, disseminated 
      mycobacteriosis, most frequently caused by members of Mycobacterium avium complex 
      (MAC), is mostly manifested in the last stage, AIDS, with extremely severe 
      immunodeficiency, or in immune reconstitution inflammatory syndrome (IRIS), 
      shortly after initiation of antiretroviral therapy. From the beginning, the 
      patient's condition was complicated by multiple simultaneous severe opportunistic 
      infections which, together with gradually progressing atypical mycobacteriosis, 
      resulted in overall exhaustion of the organism. The adverse prognosis of these 
      infections is significantly influenced by prolonged diagnosis based on culture 
      detection of slow-growing mycobacteria. In the above patient, the lethal course 
      was contributed to by resistance to commonly used antitubercular drugs which was 
      only detected post mortem due to time-consuming susceptibility tests.
FAU - Havlickova, Katerina
AU  - Havlickova K
AD  - Clinic of Infectious Medicine, Masaryk University, St. Anne's University Hospital 
      Brno, Czech Republic. havlickovak@gmail.com
FAU - Snopkova, Svatava
AU  - Snopkova S
FAU - Polak, Pavel
AU  - Polak P
FAU - Bohata, Sarka
AU  - Bohata S
FAU - Holcikova, Alena
AU  - Holcikova A
FAU - Svobodova, Jana
AU  - Svobodova J
FAU - Machacek, Ctirad
AU  - Machacek C
FAU - Husa, Petr
AU  - Husa P
LA  - cze
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Diseminovana infekce Mycobacterium avium u pacienta s nove zjistenou HIV infekci.
PL  - Czech Republic
TA  - Klin Mikrobiol Infekc Lek
JT  - Klinicka mikrobiologie a infekcni lekarstvi
JID - 101189112
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*diagnosis
MH  - Adult
MH  - Humans
MH  - Male
MH  - Mycobacterium avium-intracellulare Infection/complications/*diagnosis
EDAT- 2011/07/23 06:00
MHDA- 2011/08/31 06:00
CRDT- 2011/07/23 06:00
PHST- 2011/07/23 06:00 [entrez]
PHST- 2011/07/23 06:00 [pubmed]
PHST- 2011/08/31 06:00 [medline]
PST - ppublish
SO  - Klin Mikrobiol Infekc Lek. 2011 Jun;17(3):92-5.