PMID- 21783475
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110725
IS  - 1382-6689 (Print)
IS  - 1382-6689 (Linking)
VI  - 19
IP  - 1
DP  - 2005 Jan
TI  - Responses of the antioxidant defenses of the Goldfish Carassius auratus, exposed 
      to 2,4-dichlorophenol.
PG  - 185-90
LID - 10.1016/j.etap.2004.07.001 [doi]
AB  - Goldfish Carassius auratus were exposed to 0.1mg/l of 2,4-dichlorophenol 
      (2,4-DCP), widely used as transportation power in China, for 2, 5, 10, 20 and 40 
      days, while one control group was designated for each exposure group. Antioxidant 
      defenses consisting of contents of reduced glutathione (GSH) and glutathione 
      disulfide (GSSG) and activities of superoxide dismutase (SOD), catalase (CAT), 
      glutathione reductase (GR), selenium-dependent glutathione peroxidase (Se-GPx) 
      and glutathione S-transferase (GST) in liver of freshwater fish were determined 
      and the GSH-GSSG ratio and content of tGSH (total glutathione) were calculated. 
      In the present study, the role of hepatic antioxidant defenses was evaluated and 
      the possible poisoning mechanism of fish can be explained as an oxidative stress 
      mechanism. In addition, hepatic SOD and GSH, especially tGSH, were sensitive to 
      2,4-DCP contamination and thus, can possibly be used in early assessment of 
      2,4-DCP-dominant polluted aquatic ecosystems.
FAU - Zhang, J F
AU  - Zhang JF
AD  - Department of Earth Sciences, Nanjing University, Nanjing 210093, People's 
      Republic of China.
FAU - Liu, H
AU  - Liu H
FAU - Sun, Y Y
AU  - Sun YY
FAU - Wang, X R
AU  - Wang XR
FAU - Wu, J C
AU  - Wu JC
FAU - Xue, Y Q
AU  - Xue YQ
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Environ Toxicol Pharmacol
JT  - Environmental toxicology and pharmacology
JID - 9612020
EDAT- 2005/01/01 00:00
MHDA- 2005/01/01 00:01
CRDT- 2011/07/26 06:00
PHST- 2004/03/25 00:00 [received]
PHST- 2004/07/09 00:00 [accepted]
PHST- 2011/07/26 06:00 [entrez]
PHST- 2005/01/01 00:00 [pubmed]
PHST- 2005/01/01 00:01 [medline]
AID - S1382-6689(04)00109-7 [pii]
AID - 10.1016/j.etap.2004.07.001 [doi]
PST - ppublish
SO  - Environ Toxicol Pharmacol. 2005 Jan;19(1):185-90. doi: 
      10.1016/j.etap.2004.07.001.