PMID- 21788021
OWN - NLM
STAT- MEDLINE
DCOM- 20111024
LR  - 20110826
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1218
IP  - 37
DP  - 2011 Sep 16
TI  - Modelling of elution-extrusion counter-current chromatography using perfect 
      replacement approach.
PG  - 6412-8
LID - 10.1016/j.chroma.2011.07.007 [doi]
AB  - Basing on the perfect replacement approach the equilibrium cell model is 
      developed to describe the separation process in elution-extrusion counter-current 
      chromatography (EECCC). As is known, EECCC consists of three steps: classical 
      elution, sweeping elution, and extrusion. The perfect replacement approach means 
      that during sweeping elution step, the mobile phase contained in the column moves 
      and interacts with the "old" stationary phase in the same mode as during the 
      classical elution step; the "new" and "old" stationary phases do not mix; and 
      after the contacting with the mobile phase the concentration of solutes in the 
      "old" stationary phase remains constant and this stationary phase volume is 
      pushed ahead to the exit of the column. Equations are presented allowing the 
      simulation of the chromatogram of solutes eluted from the column with the mobile 
      phase during the elution period and the chromatogram of solutes pushed out of the 
      column with the stationary phase during the extrusion period of EECCC. These 
      equations can help to choose the optimal conditions for conducting 
      elution-extrusion counter-current chromatography.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Kostanyan, Artak E
AU  - Kostanyan AE
AD  - Kurnakov Institute of General & Inorganic Chemistry, Russian Academy of Sciences, 
      Leninsky Prospekt 31, Moscow 119991, Russia. kost@igic.ras.ru
LA  - eng
PT  - Journal Article
DEP - 20110712
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Solvents)
SB  - IM
MH  - Algorithms
MH  - *Countercurrent Distribution
MH  - *Models, Chemical
MH  - Solvents
EDAT- 2011/07/27 06:00
MHDA- 2011/10/25 06:00
CRDT- 2011/07/27 06:00
PHST- 2011/03/02 00:00 [received]
PHST- 2011/06/27 00:00 [revised]
PHST- 2011/07/03 00:00 [accepted]
PHST- 2011/07/27 06:00 [entrez]
PHST- 2011/07/27 06:00 [pubmed]
PHST- 2011/10/25 06:00 [medline]
AID - S0021-9673(11)00974-5 [pii]
AID - 10.1016/j.chroma.2011.07.007 [doi]
PST - ppublish
SO  - J Chromatogr A. 2011 Sep 16;1218(37):6412-8. doi: 10.1016/j.chroma.2011.07.007. 
      Epub 2011 Jul 12.